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  4. Update on the long-term survival of persons who are ventilator dependent after spinal cord injury

Update on the long-term survival of persons who are ventilator dependent after spinal cord injury

The Journal of Spinal Cord Medicine, 2024 · DOI: 10.1080/10790268.2022.2118489 · Published: January 1, 2024

Spinal Cord InjuryPulmonologyPublic Health

Simple Explanation

This study updates previous research on the survival rates of individuals with spinal cord injuries who rely on ventilators. The research team analyzed a larger dataset spanning from 1973 to 2019 to provide more current survival estimates. The study focused on adults aged 18 or older who had survived at least one year after their injury and were permanently ventilator dependent. The researchers used statistical models to determine mortality rates and life expectancies based on factors like age and injury severity. The findings indicate that survival rates for this population have not significantly improved since 1980. The life expectancy data provides updated estimates based on current mortality information.

Study Duration
1973-2019
Participants
459 persons with spinal cord injury, ventilator dependent
Evidence Level
Not specified

Key Findings

  • 1
    Survival has not improved since 1980 in the C1-C5A group (individuals with injuries to the first through fifth cervical vertebrae and classified as complete injuries).
  • 2
    The final survival model contained terms for age (HR = 1.047 per year of age older than 40, P < 0.001), level/grade (C1-C5A versus others: HR = 1.46, P = 0.002), and time since injury (1.0–3.0 years post injury versus later years: HR = 1.95; P < 0.001).
  • 3
    Updated life expectancies for persons with incomplete or C6 or lower level injuries were modestly lower than those of the prior study, reflecting that mortality increased in this group in the interim.

Research Summary

This study updates a prior analysis of long-term survival in ventilator-dependent individuals with spinal cord injury using a larger dataset and longer follow-up period. The analysis found that survival rates have not significantly improved since 1980 for individuals with high-level cervical injuries (C1-C5A) requiring ventilator support. Life expectancy estimates were updated based on current mortality data, and the study highlights differences in survival outcomes compared to other studies and the general population.

Practical Implications

Realistic Expectations

Provides updated life expectancy estimates for ventilator-dependent SCI patients, allowing for more informed discussions and planning.

Resource Allocation

Highlights the ongoing need for specialized care and resources for this population, particularly given the lack of improvement in survival rates.

Future Research

The reported causes of death (respiratory, infective, heart disease) points towards key areas for further investigation and intervention.

Study Limitations

  • 1
    The data is limited to individuals who were ventilator-dependent at discharge from inpatient rehabilitation, potentially excluding those who became ventilator-dependent later.
  • 2
    Approximately 10% of persons who are coded as being long-term ventilator-dependent at discharge are subsequently weaned over the next few years, leading to slight overestimates in life expectancies.
  • 3
    The study focuses on a specific population (those surviving at least one year post-injury) and may not be generalizable to all ventilator-dependent SCI patients.

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