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  4. Ultrasound Measurements of Rectus Femoris and Locomotor Outcomes in Patients with Spinal Cord Injury

Ultrasound Measurements of Rectus Femoris and Locomotor Outcomes in Patients with Spinal Cord Injury

Life, 2022 · DOI: 10.3390/life12071073 · Published: July 18, 2022

Spinal Cord InjuryMedical ImagingRehabilitation

Simple Explanation

This study investigates the relationship between the characteristics of the rectus femoris muscle, measured by ultrasound, and the ability of patients with incomplete spinal cord injuries to regain movement and walking ability after rehabilitation. The study found that thicker rectus femoris muscles and lower levels of fat within the muscle, as measured by ultrasound, were associated with better muscle function and walking ability at the time of discharge from inpatient rehabilitation. These findings suggest that ultrasound measurements could be a useful tool for assessing muscle health and predicting functional outcomes in patients with spinal cord injuries, potentially helping to guide rehabilitation strategies.

Study Duration
From 1 January 2020 to 6 June 2021
Participants
40 patients with incomplete spinal cord injury
Evidence Level
Prospective cohort study

Key Findings

  • 1
    Rectus femoris muscle thickness was significantly correlated with discharge LEMS (Spearman’s rho = 0.448; p = 0.004), FIM motor subscale (Spearman’s rho = 0.595; p < 0.001), FIM walk subscale (Spearman’s rho = 0.621; p < 0.001) and WISCI II (Spearman’s rho = 0.531; p < 0.001).
  • 2
    The rectus femoris echo intensity was also significantly correlated with discharge LEMS (Spearman’s rho = −0.345; p = 0.029), FIM motor subscale (Spearman’s rho = −0.413; p = 0.008), FIM walk subscale (Spearman’s rho = −0.352; p = 0.026), and WISCI II (Spearman’s rho = −0.355; p = 0.025).
  • 3
    A relationship exists between rectus femoris muscle ultrasonographic characteristics and muscle function and ambulatory outcomes after inpatient rehabilitation.

Research Summary

This prospective cohort study investigated the correlation between rectus femoris muscle thickness and echo intensity, measured by ultrasound, and functional outcomes in 40 patients with incomplete spinal cord injury during inpatient rehabilitation. The study found significant positive correlations between rectus femoris muscle thickness and discharge LEMS, FIM motor subscale, FIM walk subscale, and WISCI II scores, indicating that greater muscle thickness is associated with better functional and ambulatory outcomes. Conversely, rectus femoris echo intensity showed significant negative correlations with the same functional outcome measures, suggesting that lower echo intensity (less intramuscular fat) is associated with improved muscle function and walking ability.

Practical Implications

Rehabilitation Guidance

Ultrasound measurements of the rectus femoris can potentially guide rehabilitative interventions targeted at inducing muscle hypertrophy and architectural changes.

Assessment Tool

Rectus femoris muscle thickness and echo intensity may be a valid method to assess muscle function and ambulatory outcomes during inpatient rehabilitation.

Prognostic Indicator

Ultrasound muscle measurements are potentially useful in assessing muscle wasting and function in patients with spinal cord injury.

Study Limitations

  • 1
    The study did not measure other muscle function outcomes such as muscle strength or torque.
  • 2
    Longitudinal changes in the rectus femoris parameters were not studied to determine if they were a determinant of functional outcomes.
  • 3
    The extent of spasticity, which may affect muscle echo intensity, was not measured.

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