Treatment of spinal cord injury by transplantation of cells via cerebrospinal fluid

This review discusses the potential of cell transplantation via cerebrospinal fluid (CSF) for treating spinal cord injuries (SCI). It highlights the safety and convenience of this method, especially for multiple lesions in the central nervous system (CNS), as it avoids open lesions. However, the review also addresses the controversies surrounding its effectiveness in promoting axonal regeneration and functional recovery after SCI. Questions remain regarding the mechanisms of functional recovery, optimal timing for transplantation, and the best cell types to use. The article summarizes the current understanding of cell transplantation via CSF for SCI treatment, aiming to explore its role in promoting axonal regeneration and functional restoration in the CNS following spinal cord injury.

• 1
  Cell transplantation via CSF is a safe and convenient method for treating SCI, particularly suitable for multiple CNS lesions because it does not involve open lesions.
• 2
  Transplantation of cells via CSF can be useful for transplantation of cells and offers hope for the patients suffered from spinal cord injures.
• 3
  Studies suggest that cells transplanted via CSF can survive and function without obvious harmful effects at the injection site, and may even migrate to lesion sites and integrate into injured spinal cord tissues.