Transplantation of neural stem cells, Schwann cells and olfactory ensheathing cells for spinal cord injury: a Web of Science-based literature analysis

Neural Regen Res, 2012 · DOI: 10.3969/j.issn.1673-5374.2012.35.010 · Published: December 1, 2012

Spinal Cord Injury Regenerative Medicine Neurology

Simple Explanation

This study analyzes research trends in cell transplantation for spinal cord injury using neural stem cells, Schwann cells, and olfactory ensheathing cells. The analysis is based on publications indexed in the Web of Science from 2002 to 2011, focusing on publication year, journals, institutions, and highly cited papers. The study aims to provide insights into the global research landscape and the increasing importance of these cell types in treating spinal cord injury.

Study Duration

10 Years

Participants

Not specified

Evidence Level

Not specified

Key Findings

1
The number of publications on neural stem cells, Schwann cells, and olfactory ensheathing cells for spinal cord injury increased over the 10-year period.
2
Most papers appeared in journals focusing on neurology, such as Journal of Neurotrauma, Experimental Neurology, and Glia.
3
Research institutions publishing on these topics were mostly in the USA, Canada, the UK, and other countries.

Research Summary

This study performed a bibliometric analysis of studies on transplantation of neural stem cells, Schwann cells and olfactory ensheathing cells for spinal cord injury published from 2002 to 2011 retrieved from the Web of Science. The study analyzed the publication year, journals, institutions and highly cited papers related to the use of neural stem cells, Schwann cells, and olfactory ensheathing cells to repair spinal cord injury. The analysis identified research trends, indicating an increase in publications over the 10-year period and highlighting key journals and institutions involved in this research area.

Practical Implications

Future Research Directions

Combine cell transplantation with genetic and tissue engineering techniques.

Microenvironment Creation

Explore multiple cell types transplanted jointly to improve spinal cord repair.

Cell Source Identification

Identify suitable seed cell sources to address cell differentiation, immunogenicity, and regulation issues.

Study Limitations

1
The study is limited to publications indexed in the Web of Science.
2
The analysis relies on bibliometric data and does not assess the quality of the research.
3
The study period is limited to 2002-2011, and trends may have changed since then.

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