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  4. Thoracoscopic intercostal to phrenic nerve transfer for diaphragmatic reanimation in a child with tetraplegia

Thoracoscopic intercostal to phrenic nerve transfer for diaphragmatic reanimation in a child with tetraplegia

The Journal of Spinal Cord Medicine, 2021 · DOI: 10.1080/10790268.2019.1585706 · Published: March 1, 2019

Spinal Cord InjuryPulmonologyNeurology

Simple Explanation

This case report describes a new surgical technique to help a child with tetraplegia (paralysis in all four limbs) breathe more easily. The technique involves transferring a nerve from the chest wall (intercostal nerve) to the nerve that controls the diaphragm (phrenic nerve). The goal of this surgery is to reanimate the diaphragm, which is the main muscle used for breathing. By restoring the function of the diaphragm, the patient may be able to reduce or eliminate their dependence on a ventilator. The procedure was performed using minimally invasive techniques (thoracoscopy), which involves making small incisions in the chest and using a camera and specialized instruments to perform the surgery.

Study Duration
2 Years
Participants
A 5-year-old female with traumatic tetraplegia
Evidence Level
Case Report

Key Findings

  • 1
    The patient, a 5-year-old female with tetraplegia and ventilator dependence, was able to achieve ventilator independence two years after undergoing thoracoscopic intercostal to phrenic nerve transfer.
  • 2
    Post-operative M-mode ultrasonography showed marked improvement with diaphragmatic excursion of 2.1 cm on the left and 3 cm on the right.
  • 3
    The described thoracoscopic approach for nerve transfer and pacing was found to be both safe and effective for restoring innervation of the diaphragm in a child.

Research Summary

This case report presents a novel approach of thoracoscopic nerve mobilization and phrenic to intercostal nerve transposition to restore innervation of the diaphragm in a child with tetraplegia. The patient, who was previously ventilator-dependent, achieved ventilator independence two years after the procedure. The authors recommend this minimally invasive procedure as the preferred approach to reanimate the diaphragm in similar cases.

Practical Implications

Minimally Invasive Approach

Thoracoscopic nerve transfer offers a less invasive alternative to traditional thoracotomy for diaphragmatic reanimation.

Improved Quality of Life

Achieving ventilator independence can lead to improvements in mobility, speech, eating, and overall quality of life for patients with tetraplegia.

Potential for Broader Application

This technique may be applicable to other pediatric patients with diaphragmatic paralysis due to lower motor neuron injuries.

Study Limitations

  • 1
    Single case report limits generalizability.
  • 2
    Limited follow-up data on additional cases performed since this operation.
  • 3
    Long-term efficacy of the procedure needs further evaluation.

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