Spinal Cord Research Help
AboutCategoriesLatest ResearchContact
Subscribe
Spinal Cord Research Help

Making Spinal Cord Injury (SCI) Research Accessible to Everyone. Simplified summaries of the latest research, designed for patients, caregivers and anybody who's interested.

Quick Links

  • Home
  • About
  • Categories
  • Latest Research
  • Disclaimer

Contact

  • Contact Us
© 2025 Spinal Cord Research Help

All rights reserved.

  1. Home
  2. Research
  3. Spinal Cord Injury
  4. The presence of Candida parapsilosis with intrathecal baclofen pump in a person with high cervical spinal cord injury; infection or colonization? A Case Report

The presence of Candida parapsilosis with intrathecal baclofen pump in a person with high cervical spinal cord injury; infection or colonization? A Case Report

Spinal Cord Series and Cases, 2023 · DOI: https://doi.org/10.1038/s41394-023-00610-5 · Published: October 23, 2023

Spinal Cord InjuryImmunologyNeurology

Simple Explanation

Intrathecal baclofen (ITB) therapy is used to treat spasticity from spinal cord injuries, but it can lead to complications like infections. This report describes a patient with a spinal cord injury who had repeated infections related to his ITB pump, including one involving Candida parapsilosis. The case raises questions about whether the presence of Candida around the pump represents an infection or simple colonization, which impacts treatment decisions.

Study Duration
Not specified
Participants
Adult male patient with traumatic SCI
Evidence Level
Case Report

Key Findings

  • 1
    A patient with SCI and an ITB pump developed a pump pocket infection with methicillin-sensitive Staphylococcus aureus, diphtheroids, and Candida parapsilosis.
  • 2
    The patient's cerebrospinal fluid (CSF) tested positive for C. parapsilosis after a side port study of the baclofen pump was performed.
  • 3
    Despite treatment, the patient required removal of the ITB pump, followed by reimplantation after a period of oral baclofen therapy.

Research Summary

This case report presents the instance of a patient with a spinal cord injury developing an ITB pump infection involving Candida parapsilosis. The case highlights the diagnostic challenges in distinguishing between infection and colonization in ITB pump-related complications. The report emphasizes the importance of thorough evaluation and management of ITB pump infections, potentially requiring pump removal and reimplantation.

Practical Implications

Infection Control Protocols

Reinforces the need for strict adherence to infection control protocols during ITB pump implantation, replacement, and refill procedures.

Differential Diagnosis

Clinicians should consider fungal organisms like Candida parapsilosis in the differential diagnosis of ITB pump infections, especially in patients with risk factors.

Monitoring and Evaluation

Regular monitoring of patients with ITB pumps for signs of infection, including CRP levels and CSF analysis, is crucial for early detection and intervention.

Study Limitations

  • 1
    Single case report limits generalizability.
  • 2
    Difficulty in differentiating between infection and colonization.
  • 3
    Lumbar puncture was not possible, potentially limiting CSF analysis.

Your Feedback

Was this summary helpful?

Back to Spinal Cord Injury