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  4. The effect of high-frequency repetitive transcranial magnetic stimulation on motor recovery and gait parameters in chronic incomplete spinal cord injury: A randomized-controlled study

The effect of high-frequency repetitive transcranial magnetic stimulation on motor recovery and gait parameters in chronic incomplete spinal cord injury: A randomized-controlled study

Turk J Phys Med Rehab, 2023 · DOI: 10.5606/tftrd.2023.11585 · Published: June 6, 2023

Spinal Cord InjuryNeurologyRehabilitation

Simple Explanation

This study investigates whether high-frequency repetitive transcranial magnetic stimulation (rTMS) can improve walking ability and leg motor function in people with long-term, traumatic incomplete spinal cord injury (iSCI). Participants were divided into two groups: one receiving real rTMS and the other receiving sham rTMS. Both groups also underwent gait training exercises. The study found that the group receiving real rTMS showed significant improvements in walking speed and leg motor function compared to the sham group.

Study Duration
October 2015 and April 2017
Participants
28 individuals (20 males, 8 females) with chronic (>1 year) traumatic iSCI
Evidence Level
Level 1: Double-blind, sham-controlled, randomized study

Key Findings

  • 1
    Real rTMS significantly improved walking speed compared to baseline.
  • 2
    LEMS scores significantly increased in the real rTMS group compared to the sham group at both three and five weeks.
  • 3
    The 10-m walking test result significantly improved compared to baseline in the real rTMS group.

Research Summary

This study examined the effect of high-frequency rTMS on gait parameters and lower extremity motor recovery in individuals with chronic traumatic iSCI. The real rTMS group showed significant improvements in walking speed, LEMS score, and 10-m walking test after treatment compared to baseline, with LEMS improvements significantly greater than the sham group. The study concludes that rTMS can be a therapeutic aid to conventional physiotherapy for motor recovery in chronic iSCI.

Practical Implications

Clinical Practice

rTMS can be used as an adjuvant therapy to conventional physiotherapy in the rehabilitation of patients with iSCI.

Future Research

Further studies are needed to confirm the criteria for selecting appropriate participants and to determine the optimal time for rTMS after SCI.

Treatment Strategies

Motor improvement after rTMS on walking in larger cohorts can be further illustrated

Study Limitations

  • 1
    Short follow-up time
  • 2
    Unmeasured lower extremity MEP values
  • 3
    Relatively small sample size

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