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  4. Strike Out: A Case Report of Glioblastoma in a Collegiate Softball Player

Strike Out: A Case Report of Glioblastoma in a Collegiate Softball Player

Cureus, 2023 · DOI: 10.7759/cureus.44486 · Published: August 31, 2023

OncologyNeurologyOrthopedics

Simple Explanation

A 20-year-old female Division I softball player was diagnosed with glioblastoma multiforme (GBM), an aggressive brain cancer. Initially, she presented with numbness in her left hand, leading to a series of tests. The diagnosis was confirmed after an MRI revealed a mass in the right parietal lobe of her brain. The athlete underwent a treatment plan involving surgical removal of the tumor, followed by radiation and chemotherapy. Despite these aggressive treatments, GBM remains difficult to treat due to its resistance to therapies and high likelihood of recurrence. Throughout her treatment, the athlete received support from her university's medical staff, including physical therapists and psychologists, as well as her teammates and coaches. Although she was unable to continue her softball career, she returned to school and continues to receive ongoing medical care.

Study Duration
Not specified
Participants
One 20-year-old female Division I softball player
Evidence Level
Level 4: Case Report

Key Findings

  • 1
    The initial presentation of GBM in this athlete was atypical, mimicking nerve-related issues in the upper extremity. This highlights the importance of considering a broad differential diagnosis, including brain tumors, even in young, athletic individuals with seemingly musculoskeletal symptoms.
  • 2
    The case underscores the challenges of treating GBM due to its aggressive nature and resistance to conventional therapies like radiation and chemotherapy. It emphasizes the need for ongoing research and development of novel treatment strategies.
  • 3
    The athlete benefited from a multidisciplinary support system at her university, which included medical, psychological, and athletic personnel. This highlights the importance of comprehensive support for athletes facing serious medical conditions that impact their careers and overall well-being.

Research Summary

This case report describes the diagnosis and treatment of glioblastoma multiforme (GBM) in a 20-year-old Division I softball player. The athlete initially presented with numbness in her left hand, leading to the eventual discovery of a brain tumor. The treatment involved surgical resection, radiation, and chemotherapy, with ongoing support from the university's medical and athletic staff. Despite the aggressive treatment, the athlete was unable to return to competitive softball but was able to resume her studies. The case highlights the importance of considering a broad differential diagnosis in athletes with neurological symptoms, as well as the challenges and the importance of multidisciplinary support in managing GBM.

Practical Implications

Diagnostic Awareness

Maintain a broad differential diagnosis, including brain tumors, when evaluating athletes with upper extremity neurological symptoms.

Multidisciplinary Support

Provide comprehensive support to athletes diagnosed with serious illnesses, including medical, psychological, and athletic resources.

Treatment Strategies

Recognize the limitations of current GBM treatments and the need for ongoing research into novel therapies.

Study Limitations

  • 1
    Single case report limits generalizability.
  • 2
    Lack of long-term follow-up data.
  • 3
    Specific to a young, athletic population.

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