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  4. Spinal cord protection by normothermic artery bypass and visceral-anastomosis-first strategy in thoracoabdominal aortic aneurysm repair

Spinal cord protection by normothermic artery bypass and visceral-anastomosis-first strategy in thoracoabdominal aortic aneurysm repair

BMC Cardiovascular Disorders, 2025 · DOI: https://doi.org/10.1186/s12872-025-04710-y · Published: March 27, 2025

Spinal Cord InjuryCardiovascular ScienceSurgery

Simple Explanation

This study addresses spinal cord injury, a severe complication of thoracoabdominal aortic aneurysm (TAAA) surgery. It introduces and assesses a new surgical strategy—normothermic artery bypass and visceral-anastomosis-first—aimed at reducing this risk by prioritizing blood supply to vital organs and the spinal cord during the repair process. The new surgical strategy involves first reconstructing visceral and distal vessels while maintaining blood supply to the spinal cord through intercostal arteries. This is followed by reconstructing the intercostal arteries and completing the proximal anastomosis, ensuring the spinal cord receives the longest possible duration of physiological blood supply. The study compared this new strategy to normothermic iliac artery perfusion, focusing on early postoperative complications and the protective effects on visceral organs, particularly the spinal cord. The results indicated a significantly lower incidence of paraplegia and reduced need for postoperative mechanical ventilation with the new approach.

Study Duration
July 2019 to December 2023
Participants
113 patients with TAAA of Crawford types II and III
Evidence Level
Not specified

Key Findings

  • 1
    The incidence of paraplegia was significantly lower in the NABP group (0.00%) compared to the NIP group (9.72%), with a p-value of 0.047.
  • 2
    The duration of postoperative mechanical ventilation was significantly lower in the NABP group compared to the NIP group (p = 0.004).
  • 3
    The incidence of gastrointestinal adverse events was significantly lower in the NABP group (7.32%) compared to the NIP group (45.83%), with a p-value less than 0.001.

Research Summary

This retrospective study compared a novel surgical strategy, normothermic artery bypass and visceral-anastomosis-first (NABP), to normothermic iliac perfusion (NIP) for thoracoabdominal aortic aneurysm (TAAA) repair. The NABP strategy prioritizes reconstruction of visceral vessels and intercostal arteries to maintain spinal cord blood supply. Results showed that the NABP group experienced significantly lower rates of paraplegia and gastrointestinal complications, as well as reduced duration of postoperative mechanical ventilation. The study concludes that the NABP strategy is a promising approach for TAAA repair, potentially reducing the risk of spinal cord injury and improving postoperative outcomes. Further prospective studies with larger cohorts are recommended to validate these findings.

Practical Implications

Reduced Spinal Cord Injury

The normothermic artery bypass and visceral-anastomosis-first strategy shows potential in significantly reducing the risk of paraplegia, a devastating complication of TAAA repair.

Improved Postoperative Recovery

The study suggests that prioritizing visceral vessel reconstruction leads to reduced gastrointestinal complications and a shorter duration of mechanical ventilation, contributing to faster patient recovery.

Optimized Surgical Approach

The findings advocate for a shift in surgical technique, emphasizing the importance of maintaining physiological blood supply to the spinal cord throughout the TAAA repair process.

Study Limitations

  • 1
    Small sample size necessitating a larger number of patients in future studies
  • 2
    Surgical variations among different cases may have an impact on outcomes
  • 3
    Generalizability of the results to other institutions may be limited

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