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  4. Spinal cord injury as a result of Staphylococcus aureus pyogenic spinal infection complicating infected atopic eczema: two case reports

Spinal cord injury as a result of Staphylococcus aureus pyogenic spinal infection complicating infected atopic eczema: two case reports

Spinal Cord Series and Cases, 2023 · DOI: https://doi.org/10.1038/s41394-023-00599-x · Published: January 1, 2023

Spinal Cord InjuryImmunologyDermatology

Simple Explanation

Pyogenic spinal infections (PSI) are a rare cause of spinal cord injury (SCI). Staphylococcus aureus is the most common causative organism. Atopic eczema can lead to a breakdown of the skin’s natural barrier function, allowing bacterial colonisation and infection. Bacteria from the skin can then spread to the spine. This paper presents two cases where patients developed spinal cord injuries due to spinal infections caused by Staphylococcus aureus, which originated from infected atopic eczema.

Study Duration
Not specified
Participants
Two patients with SCI secondary to PSI and infected atopic eczema
Evidence Level
Level 4: Case Reports

Key Findings

  • 1
    Both patients developed spinal cord injuries as a result of pyogenic spinal infections (PSI) caused by Staphylococcus aureus originating from infected atopic eczema.
  • 2
    The first patient developed incomplete tetraplegia (C3 AIS C), requiring significant assistance after discharge. The second patient had incomplete paraplegia (L3 AIS D) and was more independent at discharge.
  • 3
    The authors believe these are the only published cases of PSI and subsequent SCI caused by secondarily infected atopic eczema.

Research Summary

This paper reports two cases of spinal cord injury (SCI) resulting from pyogenic spinal infections (PSI) caused by Staphylococcus aureus, which complicated infected atopic eczema. Both patients were treated with prolonged courses of intravenous and oral antibiotics, and their neurological outcomes varied significantly, ranging from tetraplegia to paraplegia. The authors highlight the importance of awareness among medical professionals regarding the risk of PSI and subsequent SCI in patients with atopic eczema.

Practical Implications

Increased Awareness

Medical professionals should be aware of pyogenic spinal infections (PSI) as a potential complication of infected atopic eczema.

Early Diagnosis

Consider PSI in patients with eczema flare-ups presenting with back or neck pain.

Prompt Treatment

Early diagnosis and treatment of PSI can potentially mitigate the severity of spinal cord injury.

Study Limitations

  • 1
    Limited sample size (two cases)
  • 2
    Case reports do not establish causality
  • 3
    Generalizability may be limited

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