Safety and effectiveness of electromyography-induced rehabilitation treatment after epidural electrical stimulation for spinal cord injury: study protocol for a prospective, randomized, controlled trial

Neural Regeneration Research, 2023 · DOI: https://doi.org/10.4103/1673-5374.353507 · Published: April 1, 2023

Simple Explanation

This study investigates a novel rehabilitation approach, EMG-induced rehabilitation, following epidural electrical stimulation for spinal cord injury (SCI). The trial aims to assess the recovery of muscle strength, quality of life, and safety of this combined treatment. Twenty patients with SCI will be randomly assigned to either EMG-induced rehabilitation or conventional rehabilitation to compare outcomes.

Study Duration

6 months

Participants

20 patients with SCI

Evidence Level

Level I, prospective, randomized, controlled trial

Key Findings

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The primary outcome will be the evaluation of target muscle recovery using the Manual Muscle Testing grading scale.
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Secondary outcomes include modified Barthel Index scores, integrated EMG values, visual analogue scale, Spinal Cord Independence Measure scores, and modified Ashworth scale scores.
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The safety indicator will be the incidence of adverse events.

Research Summary

This study protocol outlines a randomized controlled trial to investigate the efficacy and safety of EMG-induced rehabilitation treatment after epidural electrical stimulation for spinal cord injury. Twenty patients with SCI will be randomized into two groups: an EMG-induced rehabilitation group and a control group receiving conventional rehabilitation. The study will monitor muscle strength recovery, quality of life, and safety outcomes over a 6-month period following rehabilitation treatment.

Practical Implications

Rehabilitation Strategy Development

Findings will inform the development of rehabilitation methods for SCI patients after epidural electrical stimulation.

Optimized Post-operative Methods

The study aims to determine optimal postoperative operative methods for SCI patients receiving epidural electrical stimulation.

Clinical Evidence Provision

The trial will provide scientific evidence for rehabilitation treatment of SCI.

Study Limitations

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