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  4. Routine Urine Testing at the Spinal Cord Injury Annual Evaluation Leads to Unnecessary Antibiotic Use: A Pilot Study and Future Directions

Routine Urine Testing at the Spinal Cord Injury Annual Evaluation Leads to Unnecessary Antibiotic Use: A Pilot Study and Future Directions

Arch Phys Med Rehabil, 2018 · DOI: 10.1016/j.apmr.2017.10.005 · Published: February 1, 2018

Spinal Cord InjuryImmunologyHealthcare

Simple Explanation

The study found that routine urine tests during annual checkups for veterans with spinal cord injuries often showed bacteria, but most were asymptomatic. Despite this, many veterans were given antibiotics unnecessarily. This practice goes against medical guidelines that advise against treating asymptomatic bacteriuria (ASB) to avoid antibiotic overuse and resistance. The researchers suggest that a better understanding is needed regarding why urine testing is mandated during these annual exams, and to develop better strategies to reduce unnecessary antibiotic use in this population.

Study Duration
2 Years
Participants
393 Veterans with Spinal Cord Injury
Evidence Level
Retrospective cohort study

Key Findings

  • 1
    Most positive urine cultures from SCI annual evaluations represented ASB cases.
  • 2
    More than a third of ASB cases were treated with antibiotics, against IDSA guidelines.
  • 3
    Factors predicting antibiotic use were higher age, nitrite presence on urinalysis, and urease-producing organism on culture.

Research Summary

This retrospective study examined urine testing practices and antibiotic use in veterans with spinal cord injuries (SCI) during their annual evaluations. The study revealed a high prevalence of asymptomatic bacteriuria (ASB) and a concerning rate of unnecessary antibiotic treatment for ASB, which contradicts established medical guidelines. The authors conclude that antibiotic stewardship programs are needed to optimize urine testing and antibiotic use in the SCI population, reducing the risk of antibiotic resistance.

Practical Implications

Improvement of Antibiotic Stewardship

Findings suggest a need for targeted antibiotic stewardship programs to reduce unnecessary antibiotic use in SCI patients with ASB.

Re-evaluation of Testing Guidelines

The current VHA directive recommending routine urine cultures during annual SCI evaluations should be re-evaluated in light of IDSA guidelines.

Provider Education

Educating providers on the appropriate management of ASB in SCI patients can help reduce the overuse of antibiotics.

Study Limitations

  • 1
    Retrospective chart review study
  • 2
    Data are several years old and treatment patterns may have changed
  • 3
    Describes the practice pattern of a single site

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