Role of physiotherapy in the mobilization of patients with spinal cord injury undergoing human embryonic stem cells transplantation

This study investigates how physiotherapy aids the mobilization of spinal cord injury (SCI) patients undergoing human embryonic stem cell (hESC) therapy. The research focuses on patients with paraplegia and tetraplegia and assesses their improvement based on clinical evaluations and the American Spinal Injury Association Impairment Scale (AIS). The physiotherapy program was tailored to improve the rehabilitation and quality of life of patients with SCI. It included various exercises, gait training, and the use of devices for positioning joints and mobility aids, with the treatment phase ranging from 8 to 12 weeks depending on the type of injury. The study found that combining hESC therapy with physiotherapy led to improvements in patients with SCI, as indicated by shifts in their AIS scores and reduced reliance on orthotic devices. Physiotherapy helped in training cells and preventing limb atrophy, while hESC therapy contributed to the overall improvement of patients with SCI.

• 1
  Patients with AIS score A showed improvement to score B (15%) and C (37.3%) after hESC therapy and physiotherapy.
• 2
  Patients with AIS score B improved to AIS score C (40.6%) and D (3.1%) after the combined treatment.
• 3
  Orthotic devices were modified or reduced in complexity as patients improved, demonstrating enhanced mobility and stability.