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  4. Reinnervation of Urethral and Anal Sphincters With Femoral Motor Nerve to Pudendal Nerve Transfer

Reinnervation of Urethral and Anal Sphincters With Femoral Motor Nerve to Pudendal Nerve Transfer

Neurourol Urodyn, 2011 · DOI: 10.1002/nau.21171 · Published: November 1, 2011

UrologyNeurologySurgery

Simple Explanation

This study explores a surgical technique to restore urinary and fecal continence after nerve damage. It involves transferring motor branches of the femoral nerve to the pudendal nerve, which controls the urethral and anal sphincters. The researchers tested this nerve transfer in dogs, where they first damaged the nerves controlling the bladder and sphincters. Then, they reconnected the femoral nerve branches to the pudendal nerve branches. The results showed that the transferred femoral nerve could reinnervate the urethral and anal sphincters, leading to increased sphincter pressure upon stimulation. This suggests a potential way to help patients regain control over their bladder and bowel function.

Study Duration
Not specified
Participants
9 canines
Evidence Level
Not specified

Key Findings

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    Femoral motor nerve branches can be successfully transferred to the pudendal nerve in a canine model.
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    The transferred femoral nerve can reinnervate the urethral and anal sphincters, leading to increased sphincter pressure upon stimulation.
  • 3
    Retrograde neurotracing confirmed that the transferred femoral nerve motor branches innervated the urethral and anal sphincters.

Research Summary

This study investigates the feasibility of reinnervating the urethral and anal sphincters via transfer of motor branches of the femoral nerve to the pudendal nerve in a canine model after sacral ventral root transection. The results demonstrated that nerve stimulation induced increased anal and urethral sphincter pressures in five of six transferred nerves and retrograde neurotracing confirmed reinnervation by the transferred femoral nerve motor branches. These findings suggest that this surgical procedure may allow patients with lower motor neuron lesions to regain continence.

Practical Implications

Potential Clinical Application

The femoral nerve to pudendal nerve transfer technique could be a viable surgical option for patients with lower motor neuron lesions causing neurogenic sphincteric incontinence.

Improved Quality of Life

Restoring bladder and bowel control can significantly improve the quality of life for patients with spinal cord injuries or other conditions affecting sphincter function.

Future Research

Further studies are needed to optimize the surgical technique and assess the long-term functional outcomes in human patients.

Study Limitations

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