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  4. Prevalence of Autonomic Dysreflexia in Patients with Spinal Cord Injury above T6

Prevalence of Autonomic Dysreflexia in Patients with Spinal Cord Injury above T6

BioMed Research International, 2017 · DOI: https://doi.org/10.1155/2017/2027594 · Published: October 26, 2017

Spinal Cord InjuryCardiovascular ScienceNeurology

Simple Explanation

Autonomic dysreflexia (AD) is a condition common in spinal cord injury (SCI) patients, particularly those with injuries at or above the T6 level. It involves a range of symptoms, from mild issues like headaches and sweating to severe problems such as arrhythmia and dangerously high blood pressure. Cardiovascular disease is a major concern for SCI patients, often linked to blood pressure control issues like AD. Traditional methods of diagnosing AD, such as single blood pressure checks, may not be sufficient for early and accurate detection of blood pressure instability. This study uses ambulatory blood pressure monitoring (ABPM) and a questionnaire to assess the prevalence of AD in SCI patients. ABPM provides continuous blood pressure measurements over 24 hours, allowing for a more comprehensive assessment of blood pressure instability.

Study Duration
Not specified
Participants
28 patients diagnosed with SCI above T6
Evidence Level
Not specified

Key Findings

  • 1
    The study found a high prevalence of AD among patients with SCI above T6, with 92.8% experiencing at least one AD event according to ABPM.
  • 2
    A significant number of patients (42.9%) were identified as having asymptomatic AD, highlighting the potential for underdiagnosis when relying solely on reported symptoms.
  • 3
    The study observed a loss of the typical nocturnal blood pressure dipping pattern in SCI patients, suggesting autonomic nervous system dysfunction.

Research Summary

This study investigated the prevalence of autonomic dysreflexia (AD) in patients with spinal cord injury (SCI) above the T6 level using ambulatory blood pressure monitoring (ABPM) and the Autonomic Dysfunction Following Spinal Cord Injury (ADFSCI) questionnaire. The findings revealed a high prevalence of AD, with 92.8% of patients experiencing AD events based on ABPM. Furthermore, a substantial proportion of patients (42.9%) were found to have asymptomatic AD, indicating potential underdiagnosis. The study emphasizes the necessity of early diagnosis and therapeutic interventions for managing AD in SCI patients, even in those who are asymptomatic, to mitigate the risk of long-term cardiovascular complications.

Practical Implications

Early Diagnosis of AD

Implement routine ABPM screening for SCI patients above T6, regardless of reported symptoms, to detect AD early.

Cardiovascular Risk Management

Integrate comprehensive cardiovascular risk assessment and management strategies for all SCI patients, considering the high prevalence of AD and its potential complications.

Education and Awareness

Educate medical personnel, caregivers, and individuals with SCI about the importance of timely diagnosis and management of AD to prevent life-threatening complications.

Study Limitations

  • 1
    Small sample size
  • 2
    Incomplete exclusion of causes that may induce AD
  • 3
    Limitations in the accuracy of activity records for analyzing the relationship between activities and AD onset

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