Preliminary Study of Autologous Bone Marrow Nucleated Cells Transplantation in Children With Spinal Cord Injury

This study explored the use of bone marrow cells to treat spinal cord injuries in children. Researchers wanted to see if transplanting these cells could help improve the children's condition and if the procedure was safe. The bone marrow cells were taken from the children themselves, processed, and then delivered directly into the spinal cord and bloodstream. The study found the cell transplantation to be generally safe, with some patients showing neurological improvements and a better quality of life, suggesting it could be a promising treatment for chronic spinal cord injuries in children.

• 1
  BMNC transplantation in children with complete SC injury is safe and feasible.
• 2
  Neurological improvement was observed in two patients who received multiple implantations, including improved sensation and restored functions.
• 3
  Spasticity and quality of life were improved in some patients, and skin pressure ulcers healed and did not recur.