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  4. Neurogenic Bowel in Acute Rehabilitation Following Spinal Cord Injury: Impact of Laxatives and Opioids

Neurogenic Bowel in Acute Rehabilitation Following Spinal Cord Injury: Impact of Laxatives and Opioids

Journal of Clinical Medicine, 2021 · DOI: 10.3390/jcm10081673 · Published: April 14, 2021

Spinal Cord InjuryGastroenterologyRehabilitation

Simple Explanation

Spinal cord injury can lead to neurogenic bowel dysfunction (NBD), significantly impacting quality of life. This study examines how bowel function changes during acute rehabilitation after SCI, focusing on the use of laxatives and opioids. The study found that during acute rehabilitation, individuals with SCI experienced an increase in bowel movement frequency and a decrease in fecal incontinence. Additionally, the use of laxatives and opioids was reduced from admission to discharge. The research highlights the importance of managing laxative and opioid use during SCI rehabilitation. It suggests that while these medications are often necessary, they can have negative impacts on bowel function if not carefully monitored.

Study Duration
2 Years
Participants
161 individuals with acute traumatic/non-traumatic SCI
Evidence Level
Not specified

Key Findings

  • 1
    There was an increase in the frequency of bowel movements and a decrease in the frequency of fecal incontinence from admission to discharge.
  • 2
    The number of individuals using laxatives and the number of unique laxatives taken decreased between admission and discharge.
  • 3
    There was a significant negative correlation between the average dose of opioids and the frequency of bowel movements at discharge, confirming the constipating effect of opioids.

Research Summary

This study investigated the impact of inpatient rehabilitation on bowel dysfunction in individuals with acute traumatic/non-traumatic SCI, focusing on the use of laxatives and opioids. The research found improvements in bowel function (increased bowel movement frequency and decreased fecal incontinence) during acute rehabilitation, along with a reduction in laxative and opioid use. The study also revealed a positive correlation between laxative use and fecal incontinence at discharge, and a negative correlation between opioid dose and bowel movement frequency, highlighting the complex interplay of medications and bowel function in SCI patients.

Practical Implications

Optimized Medication Management

Clinicians should carefully monitor and adjust laxative and opioid prescriptions during acute SCI rehabilitation to minimize negative impacts on bowel function.

Personalized Bowel Protocols

Individualized bowel management protocols, considering the type of SCI and medication use, are essential for effective NBD management.

Further Research Needed

Additional research is needed to study the long-term effects of laxative and opioid use on bowel dysfunction in individuals with chronic SCI.

Study Limitations

  • 1
    Small sample size, particularly for lumbosacral injuries
  • 2
    Incomplete data due to the retrospective nature of the study
  • 3
    Lack of data on factors influencing bowel function like food, oral liquid intake and satisfaction of medication use

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