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  4. Lower Body Perfusion Reduces the Morbidity of Postoperative Acute Kidney Injury in Type A Dissection: A Propensity-Matched Analysis

Lower Body Perfusion Reduces the Morbidity of Postoperative Acute Kidney Injury in Type A Dissection: A Propensity-Matched Analysis

Braz J Cardiovasc Surg, 2023 · DOI: https://doi.org/10.21470/1678-9741-2022-0190 · Published: July 1, 2023

UrologyCardiovascular ScienceSurgery

Simple Explanation

Lower body perfusion (LBP) is a technique used to provide blood perfusion to distal organs and spinal cord during circulatory arrest. The study found that LBP can significantly shorten the circulatory arrest time, thus making it possible to raise the temperature during circulatory arrest in aortic arch surgery. The research retrospectively analyzed the changes of antegrade LBP on CPB-related factors in aortic arch surgery to evaluate the impact of antegrade LBP on the prognosis of aortic arch surgery, especially on postoperative renal function.

Study Duration
May 2016 and December 2021
Participants
304 patients with acute type A aortic dissection
Evidence Level
Not specified

Key Findings

  • 1
    LBP resulted as a safe and feasible approach in aortic arch surgery.
  • 2
    LBP could significantly shorten the circulatory arrest time.
  • 3
    LBP might reduce the incidence of postoperative level I acute kidney injury.

Research Summary

This study retrospectively analyzed 304 patients with acute type A aortic dissection who underwent total aortic arch replacement combined with frozen elephant trunk implantation between May 2016 and December 2021. The patients were divided into an LBP group (n=85) and a non-LBP group (n=219). The study concluded that antegrade LBP is safe and feasible in aortic arch surgery, can significantly shorten the circulatory arrest time, and reduces the incidence of postoperative level I AKI.

Practical Implications

Surgical Technique

Antegrade LBP can be considered as a safe and feasible surgical technique in aortic arch surgery.

Patient Outcome

LBP use could reduce the incidence of postoperative level I acute kidney injury.

Clinical Practice

The study may contribute to a change in clinical practice favoring the use of LBP in aortic arch surgery to shorten circulatory arrest time and improve organ perfusion.

Study Limitations

  • 1
    Retrospective study design
  • 2
    Surgeon's influence on surgical technique
  • 3
    Lack of a prospective controlled study

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