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  4. Longitudinal study of body composition in spinal cord injury patients

Longitudinal study of body composition in spinal cord injury patients

Indian Journal of Orthopaedics, 2014 · DOI: 10.4103/0019-5413.128760 · Published: March 1, 2014

Spinal Cord InjuryPhysiologyMusculoskeletal Medicine

Simple Explanation

Spinal cord injuries often lead to bone mass loss and muscle atrophy. This study uses DEXA to monitor these changes in patients during their first year after injury. The study reveals significant decreases in bone mineral content and lean body mass, along with increases in total body fat mass, especially in the lower body. Tetraplegic patients experienced more significant decreases in arm bone mineral content and lean body mass compared to paraplegic patients, highlighting the impact of lesion level on body composition changes.

Study Duration
1 year
Participants
95 patients with acute SCI
Evidence Level
Longitudinal prospective study

Key Findings

  • 1
    There was a significant decrease in BMC (P < 0.05) and LBM (P < 0.05) and increase in total body fat mass (TBFM) and percentage fat at infra‑lesional sites.
  • 2
    The average decrease was 14.5% in BMC in lower extremities, 20.5% loss of LBM in legs and 15.1% loss of LBM in trunk, and increase of 0.2% in fat mass in legs and 17.3% increased fat in the lower limbs at 1 year.
  • 3
    The tetraplegic patients had significant decrease in arm BMC (P < 0.001), arm LBM (P < 0.01) and fat percentage (P < 0.01) compared to paraplegics.

Research Summary

This prospective longitudinal study evaluated body composition changes in 95 patients with acute SCI using DEXA during the first year post-injury. The study found a marked decrease in BMC and LBM with an increase in adiposity, with changes influenced by the level and severity of lesions as well as neurological recovery. The findings suggest the importance of monitoring and managing body composition changes early in SCI to mitigate potential health risks.

Practical Implications

Early Intervention Strategies

Implement early mobilization and rehabilitation to prevent bone loss and muscle atrophy.

Personalized Treatment Plans

Tailor interventions based on the level and severity of the spinal cord injury.

Monitoring Metabolic Health

Regularly monitor body composition to mitigate risks of microvascular diseases and fractures.

Study Limitations

  • 1
    The age may have effect on the outcomes in the present study.
  • 2
    Some patients might not have optimal rehabilitation.
  • 3
    Dietary habits not accounted for

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