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  4. Hidden cause of paralysis: tight filum terminale in spinal cord injury without radiographic abnormality

Hidden cause of paralysis: tight filum terminale in spinal cord injury without radiographic abnormality

Frontiers in Pediatrics, 2025 · DOI: 10.3389/fped.2024.1528007 · Published: January 22, 2025

Spinal Cord InjurySurgeryPediatrics

Simple Explanation

This study looks at children who have spinal cord injuries that don't show up on X-rays or CT scans, called SCIWORA. The researchers analyzed data from four children with SCIWORA, focusing on how they were injured, what symptoms they had, and how they responded to surgery. The study suggests that a tight filum terminale (a structure at the end of the spinal cord) might be the hidden cause of some SCIWORA cases, and that surgery to release it could help.

Study Duration
November 2022 to June 2024
Participants
Four children diagnosed with SCIWORA
Evidence Level
Not specified

Key Findings

  • 1
    All four patients had thoracolumbar injuries with rapid progression of symptoms, including paralysis, sensory impairment, and urinary and fecal retention.
  • 2
    Intraoperative findings in all four pediatric cases revealed spinal cord tethering, with evidence of fatty or fibrous degeneration involving the filum terminale.
  • 3
    Three patients showed varying degrees of recovery in muscle strength and/or sensory function, as well as bladder and bowel function, while one showed no significant improvement.

Research Summary

This study retrospectively analyzed the clinical data of four SCIWORA patients treated at our hospital from November 2022 to June 2024, exploring their injury mechanisms, clinical features, spinal cord imaging changes, treatment, and prognosis to provide a reference for the management of SCIWORA. The study suggests that tethered cord syndrome may be a potential underlying cause of SCIWORA, and recommends early surgical intervention for decompression and release of the tether. Timely surgery, complete decompression, and resolution of tethering, followed by duroplasty to expand the spinal canal, can significantly alleviate intraspinal pressure and enhance spinal cord perfusion.

Practical Implications

Early Surgical Intervention

Early surgical intervention is recommended for children with SCIWORA accompanied by tethered cord syndrome to aid in the recovery of neurological function.

Complete Decompression

Complete decompression and resolution of tethering are crucial during surgery to alleviate intraspinal pressure and enhance spinal cord perfusion.

Careful Evaluation of Spinal Structures

Even when the conus medullaris appears in a normal plane on imaging, it is essential to carefully evaluate the morphology of the conus, the filum terminale, and other spinal structures.

Study Limitations

  • 1
    Small sample size due to the rarity of SCIWORA.
  • 2
    Short-term follow-up period.
  • 3
    Lack of a comparative analysis with conservative treatment approaches.

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