Front. Transplant., 2023 · DOI: 10.3389/frtra.2023.1287508 · Published: December 7, 2023
This study presents the case of a 41-year-old male with a spinal cord injury who received multiple infusions of his own stem cells derived from fat tissue. Over a period of about 2.5 years, the patient received 34 infusions, which led to significant improvements in his quality of life. The patient's motor and sensory functions improved, as demonstrated by electromyography and nerve conduction velocity studies, and no serious adverse events were reported during the treatment.
Autologous HB-adMSC therapy may offer a safe and non-invasive treatment option for improving neurological function in SCI patients.
Recurrent administration of intravenous infusions of autologous HB-adMSCs resulted in improved SCIM-III scores, reflecting clinically relevant functional improvements.
Future clinical trials with a larger sample size and randomized, placebo-controlled study design should be conducted to validate the findings of this study.