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  4. Effect of nutritional status on occurrence of pneumonia after traumatic cervical spinal cord injury

Effect of nutritional status on occurrence of pneumonia after traumatic cervical spinal cord injury

Scientific Reports, 2024 · DOI: https://doi.org/10.1038/s41598-024-64121-5 · Published: June 5, 2024

Spinal Cord InjuryImmunologyNutrition & Dietetics

Simple Explanation

Pneumonia is a frequent and severe complication following cervical spinal cord injury (CSCI). This study investigates how nutritional factors influence the occurrence of pneumonia in these patients. The study found that low nutritional status, severe paralysis, and reduced lung capacity are significant risk factors for developing pneumonia after CSCI. Besides managing respiratory function, assessing and addressing nutritional needs may be crucial in preventing pneumonia linked to immune suppression caused by spinal cord injuries. Nutritional support should be promptly provided if a patient's nutritional status deteriorates post-injury.

Study Duration
October 2015 to June 2022
Participants
182 patients with acute traumatic CSCI
Evidence Level
Not specified

Key Findings

  • 1
    Low nutritional status, indicated by a PNI ≤ 38.7, was a significant risk factor for pneumonia after CSCI (OR 3.35; 95% CI 1.19–9.39).
  • 2
    Severe paralysis, indicated by a motor score ≤ 17, was also a significant risk factor for pneumonia (OR 7.13; 95% CI 2.46–20.66).
  • 3
    Low vital capacity, defined as ≤ 1300 mL, significantly affected the occurrence of pneumonia (OR 5.06; 95% CI 1.69–15.1).

Research Summary

This study investigated the effects of nutritional factors on the occurrence of pneumonia after cervical spinal cord injury (CSCI). The results showed that low nutritional status, severe paralysis, and low vital capacity were significant risk factors for pneumonia in patients with CSCI. The study concludes that nutritional assessment and intervention, in addition to respiratory management, may play key roles in preventing pneumonia associated with spinal cord injury-induced immune depression.

Practical Implications

Nutritional Assessment and Intervention

Implement early and comprehensive nutritional assessments for patients with acute traumatic CSCI to identify and address nutritional deficiencies.

Multidisciplinary Approach

Integrate nutritional care into the standard respiratory management protocols for CSCI patients to improve overall outcomes.

Early Swallowing Dysfunction Management

Focus on early diagnosis and treatment of swallowing dysfunction to improve nutritional status and reduce the risk of pneumonia.

Study Limitations

  • 1
    The severity of trauma may have affected the PNI value despite evaluating the earliest timing of blood sampling.
  • 2
    The study did not include the effect of intervention for nutrition after CSCI.
  • 3
    No previous study has identified cutoff values for respiration, paralysis, and nutritional status to predict the occurrence of pneumonia after CSCI.

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