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  4. Effect of muscle contractions on cartilage: morphological and functional magnetic resonance imaging evaluation of the knee after spinal cord injury

Effect of muscle contractions on cartilage: morphological and functional magnetic resonance imaging evaluation of the knee after spinal cord injury

Rev Bras Ortop, 2016 · DOI: http://dx.doi.org/10.1016/j.rboe.2016.01.009 · Published: February 2, 2016

Spinal Cord InjuryOrthopedics

Simple Explanation

This study investigates how the absence of muscle contractions affects knee cartilage in individuals with spinal cord injuries, even when they have some joint movement. Patients with complete spinal cord injuries underwent knee MRIs at the beginning of the study and again after six months. They also received rehabilitation with passive motion exercises. The study found that the absence of muscle contractions may harm normal knee cartilage, even with normal joint motion. More research with more patients is needed.

Study Duration
6 Months
Participants
6 patients with complete spinal cord injuries
Evidence Level
Not specified

Key Findings

  • 1
    Absence of muscle contractions seems deleterious to normal human knee cartilage.
  • 2
    Increase in T2 values observed on the six-month MRI, especially in the patellofemoral joint.
  • 3
    Patients had a normal passive range of motion, but presented articular cartilage damage.

Research Summary

The study evaluated the effect of complete absence of muscle contractions on normal human cartilage in the presence of joint motion in patients with complete spinal cord injuries. Patients underwent MRI on both knees and received rehabilitation treatment including lower-limb passive motion exercises. The absence of muscle contractions seems to be deleterious to normal human knee cartilage even in the presence of a normal range of motion.

Practical Implications

Rehabilitation Strategies

Emphasize muscle activation exercises alongside passive motion in SCI rehabilitation.

Cartilage Protection

Explore interventions to mitigate cartilage degradation in the absence of muscle contractions.

Further Research

Conduct larger studies to confirm the deleterious effects of absent muscle contractions on cartilage.

Study Limitations

  • 1
    Small sample size (only two patients completed the six-month MRI study)
  • 2
    Only two time points (time-zero and six-month MRIs)
  • 3
    Difficulty enrolling patients due to logistical challenges

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