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  4. Effect of a virtual walking and exercise-based intervention on muscle strength and activation in people with incomplete spinal cord injury

Effect of a virtual walking and exercise-based intervention on muscle strength and activation in people with incomplete spinal cord injury

Scientific Reports, 2025 · DOI: https://doi.org/10.1038/s41598-025-86845-8 · Published: January 14, 2025

Spinal Cord InjuryAssistive TechnologyRehabilitation

Simple Explanation

This study investigates whether combining virtual walking (VW) with physical exercise (PE) improves lower limb strength and muscle activation in individuals with incomplete spinal cord injury (iSCI), compared to PE alone. Participants were divided into two groups: one receiving VW and PE, and the other receiving a placebo VW and PE. Muscle strength and activation were assessed before, immediately after, and at follow-up periods after the intervention. The results showed that the group receiving VW and PE experienced greater improvements in muscle strength and activation compared to the group receiving PE alone, suggesting that VW could enhance the effects of PE in people with iSCI.

Study Duration
6 weeks of Experimental Intervention + follow ups
Participants
38 participants with incomplete spinal cord injury
Evidence Level
Randomized controlled trial

Key Findings

  • 1
    The Experimental Intervention (EI) group exhibited a general strength increase after the intervention, ranging from 16.31 to 34.72 N, and maintained this improvement for hip abduction and extension movements up to a 1-month follow-up.
  • 2
    The EI group showed an increase in muscle activation in all agonistic muscles except gastrocnemius immediately post-intervention, while also experiencing a decrease in antagonistic muscle activation for gastrocnemius and rectus femoris during specific movements.
  • 3
    The Control Intervention (CI) group only showed improvements in hip abduction and extension movements and an activation increase of agonistic muscles of hip abduction and extension, without changes in antagonistic activation.

Research Summary

This study assessed the impact of combining virtual walking (VW) therapy with a physical exercise (PE) program on lower limb strength and muscle activation in individuals with incomplete spinal cord injury (iSCI), comparing it to PE alone. The experimental group (VW + PE) showed significant overall strength improvements across assessed muscle groups immediately post-intervention and maintained improvements in hip abductors and extensors up to four weeks post-intervention. The study concludes that virtual walking can enhance the effects of physical exercise on muscle strength and activation in people with incomplete SCI, potentially prolonging the treatment's effect after it has ended.

Practical Implications

Enhanced Rehabilitation Strategies

Integrating virtual walking with physical exercise can improve rehabilitation outcomes for individuals with incomplete SCI.

Corticospinal Pathway Activation

The study underscores the importance of complementing physical exercise programs with corticospinal facilitation techniques to maximize functional capacity potential.

Home-Based Applications

The simple experimental setup emphasizes the potential for translating these findings into practical and at-home applications.

Study Limitations

  • 1
    High heterogeneity in the sample, which is not unusual when researching with people presenting spinal cord injury
  • 2
    Therapists could not be blinded due to the nature of the intervention.
  • 3
    EMG activity of adductor muscles was not recorded because the assessment position for the adductors made contact between EMG sensors impossible.

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