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  4. Early use of an implantable diaphragm pacing stimulator for a child with severe acute flaccid myelitis—a case report

Early use of an implantable diaphragm pacing stimulator for a child with severe acute flaccid myelitis—a case report

Spinal Cord Series and Cases, 2019 · DOI: 10.1038/s41394-019-0207-7 · Published: May 9, 2019

Spinal Cord InjuryNeurologyPediatrics

Simple Explanation

Acute Flaccid Myelitis (AFM) is a rare but serious condition affecting children, leading to muscle weakness and sometimes breathing difficulties. This case report explores using a diaphragm pacing system (DPS) early in a child with AFM to help her breathe. The diaphragm pacing system helped the child tolerate reduced ventilator settings and showed improved breathing ability with pacing.

Study Duration
19 weeks
Participants
A 3-year-old girl
Evidence Level
Case Report

Key Findings

  • 1
    Direct stimulation of the diaphragm demonstrated contraction even when surface electrodiagnostics did not show diaphragmatic innervation.
  • 2
    The patient was able to tolerate short bouts of reduced ventilation settings immediately following DPS placement.
  • 3
    The patient demonstrated larger tidal volumes with active pacing than without, although she remained ventilator-dependent.

Research Summary

This case report describes the early use of a diaphragmatic pacing system (DPS) in a 3-year-old girl with severe Acute Flaccid Myelitis (AFM). The DPS was implanted three weeks post-presentation, and the patient showed immediate improvement in tolerating reduced ventilation settings. The findings suggest that early DPS placement may augment diaphragm function and potentially enhance the recovery of spontaneous function in AFM patients.

Practical Implications

Early Intervention

Early assessment and intervention with DPS may improve respiratory outcomes in AFM patients.

Diagnostic Tool

Intraoperative diaphragm stimulation can be a valuable diagnostic tool when surface electrodiagnostics are inconclusive.

Potential for Enhanced Recovery

DPS may promote axonal sprouting and reinnervation, leading to improved respiratory function.

Study Limitations

  • 1
    Single case report limits generalizability
  • 2
    Long-term outcomes not yet known
  • 3
    Spontaneous recovery cannot be fully ruled out

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