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  4. Description of Bone Health Changes in a Cohort of Children With Acute Flaccid Myelitis (AFM)

Description of Bone Health Changes in a Cohort of Children With Acute Flaccid Myelitis (AFM)

Top Spinal Cord Inj Rehabil, 2022 · DOI: 10.46292/sci21-00035 · Published: January 1, 2022

Spinal Cord InjuryPediatricsMusculoskeletal Medicine

Simple Explanation

Acute flaccid myelitis (AFM) is a rare but serious condition that primarily affects children, leading to muscle weakness and sometimes paralysis. This study looks at the bone health of children with AFM. The study found that many children with AFM have low bone mass, which can increase their risk of fractures. The study also found connections between muscle mass, bone density, and how well the children could move. The findings suggest that doctors should carefully monitor the bone health of children with AFM and try to help them build and maintain muscle mass to protect their bones.

Study Duration
January 1, 2007, to December 31, 2019
Participants
79 children with AFM
Evidence Level
Not specified

Key Findings

  • 1
    A significant percentage (78%) of children with AFM in the study were diagnosed with low bone mass.
  • 2
    Lean muscle mass correlated positively with bone mass and functional performance (as measured by PAMS).
  • 3
    There was a positive correlation between ambulatory status and bone density in the lower limbs.

Research Summary

This retrospective study examined bone health changes in 79 children with AFM and found a high prevalence of low bone mass (78%) among those who had DXA scans. The study highlights the importance of monitoring bone health in children with AFM and implementing strategies to preserve bone mass and maximize muscle mass. The researchers found correlations between lean muscle mass and bone mass, functional performance, and a relationship between ambulatory status and bone density in the lower limbs.

Practical Implications

Bone Health Monitoring

Regular bone health monitoring is crucial for children with AFM.

Muscle Mass Preservation

Efforts should be made to maximize muscle mass in children with AFM.

Weight-Bearing Activities

Weight-bearing activities should be encouraged to improve bone density.

Study Limitations

  • 1
    Retrospective data collection.
  • 2
    Small sample size.
  • 3
    Descriptive and correlative statistics were used.

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