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  4. Case report: Virtual reality-based arm and leg cycling combined with transcutaneous electrical spinal cord stimulation for early treatment of a cervical spinal cord injured patient

Case report: Virtual reality-based arm and leg cycling combined with transcutaneous electrical spinal cord stimulation for early treatment of a cervical spinal cord injured patient

Frontiers in Neuroscience, 2024 · DOI: 10.3389/fnins.2024.1380467 · Published: May 17, 2024

Spinal Cord InjuryAssistive TechnologyNeurology

Simple Explanation

This case report explores a new therapy for spinal cord injury (SCI) patients involving virtual reality (VR) based arm and leg cycling combined with transcutaneous electrical spinal cord stimulation (tSCS). SCI often results in loss of motor and sensory function. The patient, a 50-year-old woman, experienced improvements in both sensory and motor abilities, as well as reduced anxiety and depression, after undergoing the combined therapy. The patient’s self-reliance and capacity to carry out everyday tasks showed ongoing enhancement, leading to the restoration of their functionality. While the results are promising, the study acknowledges limitations such as the small sample size and the potential for natural recovery to contribute to the observed improvements. Further research with larger, controlled trials is necessary.

Study Duration
6-weeks
Participants
A 50-year-old woman with cervical spinal cord injury
Evidence Level
Case Report

Key Findings

  • 1
    The patient experienced notable enhancement in both sensory and motor abilities as per the ASIA scores, indicating a positive impact of the combined therapy.
  • 2
    The patient’s anxiety and depression were reduced as measured by the Hamilton Anxiety and Hamilton Depression Tests, suggesting a positive psychological impact of the intervention.
  • 3
    The patient’s self-reliance and capacity to carry out everyday tasks showed ongoing enhancement, leading to the restoration of their functionality, as evaluated by the SCIM-III.

Research Summary

This case report presents a novel intervention combining Virtual Reality-based arm and leg cycling with transcutaneous electrical spinal cord stimulation (tSCS) for early treatment of cervical spinal cord injury (SCI). The approach aims to enhance sensory and locomotor functional recovery by activating both cerebral and limb regions. The patient showed significant improvements in motor and sensory function, psychological well-being (reduced anxiety and depression), and activities of daily living (ADL) after a 6-week intervention period. Improvements in ASIA scores, HAMA/HAMD scores, and SCIM-III scores were observed. The study acknowledges limitations such as the small sample size and the potential for natural recovery to contribute to the observed improvements, highlighting the need for future randomized controlled trials with larger sample sizes to confirm the clinical impacts.

Practical Implications

Rehabilitation Strategy

The combination therapy of VR-based cycling and tSCS presents a potential rehabilitation strategy for early-stage SCI patients.

Psychological Benefits

The intervention may reduce anxiety and depression, highlighting the importance of considering psychological well-being in SCI rehabilitation.

Functional Improvement

Improvements in ADL suggest that the therapy could improve independence and quality of life for SCI patients.

Study Limitations

  • 1
    Small sample size (single case report)
  • 2
    Uncertainty regarding the specific contribution of the intervention versus natural recovery
  • 3
    Incomplete investigation and validation of the selected tSCS stimulation parameters

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