Spinal Cord Research Help
AboutCategoriesLatest ResearchContact
Subscribe
Spinal Cord Research Help

Making Spinal Cord Injury (SCI) Research Accessible to Everyone. Simplified summaries of the latest research, designed for patients, caregivers and anybody who's interested.

Quick Links

  • Home
  • About
  • Categories
  • Latest Research
  • Disclaimer

Contact

  • Contact Us
© 2025 Spinal Cord Research Help

All rights reserved.

  1. Home
  2. Research
  3. Neurology
  4. Bulbar onset amyotrophic lateral sclerosis: A case report

Bulbar onset amyotrophic lateral sclerosis: A case report

Annals of Medicine and Surgery, 2022 · DOI: https://doi.org/10.1016/j.amsu.2022.104889 · Published: November 13, 2022

NeurologyResearch Methodology & Design

Simple Explanation

Amyotrophic lateral sclerosis (ALS) is a rare disease affecting nerve cells in the brain and spinal cord. Early diagnosis is crucial for managing bulbar onset ALS, which affects speech and swallowing. This case report details a 60-year-old female presenting with slurred speech and difficulty swallowing. Diagnostic tools like MRI, EMG, and NCS were used to confirm ALS. Effective treatment of ALS requires a team of specialists, including neurologists and speech therapists. Edaravone, an antioxidant, can help reduce neuronal injury in ALS patients.

Study Duration
Not specified
Participants
One 60-year-old female
Evidence Level
Level 4, Case Report

Key Findings

  • 1
    The presence of genioglossus muscle involvement at diagnosis implies a shorter survival for ALS patients.
  • 2
    Bulbar onset ALS can have a grave prognosis, necessitating a multidisciplinary approach for effective treatment.
  • 3
    Ruling out other pathologies before diagnosing ALS is crucial, as conditions like myasthenia gravis can mimic ALS symptoms.

Research Summary

This case report highlights the importance of early diagnosis in bulbar onset ALS, a rare and progressive neurodegenerative disease. A 60-year-old female with slurred speech and dysphagia was diagnosed with ALS using MRI, EMG, and NCS after ruling out other conditions. The report emphasizes the necessity of a multidisciplinary approach and the potential benefits of Edaravone in managing ALS, while acknowledging the grave prognosis associated with bulbar onset ALS.

Practical Implications

Early Diagnosis

Highlights the importance of early and accurate diagnosis of bulbar onset ALS to improve patient outcomes.

Multidisciplinary Care

Emphasizes the need for a collaborative approach involving neurologists, speech therapists, and other specialists in ALS management.

Treatment Options

Suggests Edaravone as a potential treatment option to counteract oxidative stress and neuronal injury in ALS patients.

Study Limitations

  • 1
    Single case report limits generalizability.
  • 2
    Short follow-up period.
  • 3
    Limited information on long-term treatment outcomes.

Your Feedback

Was this summary helpful?

Back to Neurology