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  4. Benefits of Early Surgical Treatment for Patients with Multilevel Cervical Canal Stenosis of Acute Traumatic Central Cord Syndrome

Benefits of Early Surgical Treatment for Patients with Multilevel Cervical Canal Stenosis of Acute Traumatic Central Cord Syndrome

Orthopaedic Surgery, 2023 · DOI: 10.1111/os.13904 · Published: December 1, 2023

Spinal Cord InjurySurgerySpinal Disorders

Simple Explanation

This study investigates the best treatment approach for patients with acute traumatic central cord syndrome (ATCCS) and multilevel cervical canal stenosis (CCS). It compares conservative treatment, early surgery (within 7 days), and late surgery (after 7 days). The study found that patients who underwent early surgery had better clinical function and quality of life compared to those who received conservative treatment or late surgery. Early surgery is also cost-effective. Younger patients, those with a better initial ASIA grade, and those who had early surgery experienced better outcomes. The findings suggest that early surgical intervention is beneficial for this patient population.

Study Duration
2 years minimum
Participants
93 patients with acute traumatic central cord syndrome and multilevel cervical canal stenosis
Evidence Level
Retrospective cohort study

Key Findings

  • 1
    Patients who received early surgery (≤7 days) had significantly better ASIA grade, JOA score, and recovery rate compared to those who received conservative treatment or late surgery (>7 days).
  • 2
    Early surgery was found to be cost-effective compared to conservative treatment, despite the higher initial cost.
  • 3
    Younger age, better initial ASIA grade, and earlier surgery were associated with better prognosis in patients with ATCCS and multilevel CCS.

Research Summary

This retrospective study compared conservative treatment, early surgery (≤7 days), and late surgery (>7 days) for 93 patients with acute traumatic central cord syndrome (ATCCS) and multilevel cervical canal stenosis (CCS). The study found that early surgery resulted in significantly better clinical function and living quality compared to conservative treatment and late surgery. There was no significant difference between conservative treatment and late surgery. Multivariate analysis revealed that younger age, better initial ASIA grade, and earlier surgery were associated with better prognosis. Early surgery was also found to be more cost-effective than conservative treatment.

Practical Implications

Clinical Practice

Early surgical intervention should be considered for ATCCS patients with multilevel CCS to improve clinical function and quality of life.

Cost-Effectiveness

Despite the higher initial cost, early surgery is a cost-effective treatment option compared to conservative management for this patient population.

Prognostic Factors

Age and initial ASIA grade should be considered when determining the optimal treatment strategy for ATCCS patients with multilevel CCS.

Study Limitations

  • 1
    Retrospective cohort study design
  • 2
    Relatively small sample size, especially in the early surgery group
  • 3
    Lack of sensitivity analysis and discounting in the cost-utility analysis

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