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  4. Association between swallowing disorder and prevertebral hyperintensity on magnetic resonance imaging in patients after cervical cord injury without major fracture

Association between swallowing disorder and prevertebral hyperintensity on magnetic resonance imaging in patients after cervical cord injury without major fracture

Medicine, 2023 · DOI: http://dx.doi.org/10.1097/MD.0000000000036194 · Published: December 1, 2023

Spinal Cord InjuryMedical ImagingRehabilitation

Simple Explanation

This study investigates the link between swallowing difficulties and the appearance of bright areas in the neck on MRI scans of patients with spinal cord injuries but no major bone fractures. The goal was to see if these bright areas could help predict swallowing problems. The researchers measured the size of these bright areas on MRI scans and compared them to whether or not the patients had swallowing problems requiring feeding tubes. They found that larger bright areas were linked to a higher chance of swallowing difficulties. They determined a specific size for these bright areas that could be used as a cutoff point to help identify patients at risk for swallowing problems after this type of spinal cord injury.

Study Duration
9 years
Participants
30 patients with acute CSCI without major fracture
Evidence Level
Observational Study

Key Findings

  • 1
    The incidence of swallowing disorders after CSCI in the absence of major fractures was 16.7%.
  • 2
    The HIA was significantly higher in the swallowing disorder group (median, 409.0 mm2) than in the non- swallowing disorder group (median, 159.1 mm2) (P = .04).
  • 3
    The optimal cutoff point of the HIA was measured at 203.2 mm2 with 80.0% and 20.0% sensitivity and specificity, respectively.

Research Summary

This retrospective observational study aimed to clarify the association between swallowing disorder and prevertebral hyperintensity on MRI in patients with cervical spinal cord injury (CSCI) without a major fracture. The incidence of swallowing disorder after CSCI was 16.7%. The prevertebral hyperintensity area on MRI for swallowing disorder in patients after cervical cord injury without skeletal injury is associated with swallowing disorder.

Practical Implications

Predictive Biomarker

The prevertebral hyperintensity area on MRI can serve as a predictive biomarker for swallowing disorders in patients with CSCI without major fractures.

Early Intervention

Identifying a cutoff point (203.2 mm2) allows for earlier intervention and management of dysphagia in at-risk patients.

Diagnostic Utility

The study supports the use of STIR-MRI as a valuable diagnostic tool for evaluating soft tissue damage associated with swallowing disorders after CSCI.

Study Limitations

  • 1
    Small sample size
  • 2
    Lack of evaluation of the time course of swallowing disorders using MRI after the injury
  • 3
    Unclear mechanisms underlying swallowing disorders after CSCI

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