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  4. An unusual cause of chronic neuropathic pain: report of a case of multiple intradural spinal arachnoid cysts and review of the literature

An unusual cause of chronic neuropathic pain: report of a case of multiple intradural spinal arachnoid cysts and review of the literature

Acta Neurochirurgica, 2023 · DOI: 10.1007/s00701-023-05732-1 · Published: August 1, 2023

Pain ManagementSurgerySpinal Disorders

Simple Explanation

Spinal arachnoid cysts (SACs) are rare occurrences that have been classified as part of the larger group of meningeal pathologies called spinal meningeal cysts. This report is, to the best of our knowledge, the first to describe the long-term outcomes in a patient with multiple de novo forming and recurring intradural SACs. The patient developed several cysts extending intradurally from the posterior fossa to the lower thoracic levels. The etiology of the condition could not be defined.

Study Duration
10 Years
Participants
1 Female patient
Evidence Level
Case Report and Literature Review

Key Findings

  • 1
    Multiple intradural SACs are rare, with only six cases being reported in the literature, including the one hereby presented.
  • 2
    Cyst recurrence may be rapid, and it is important to consider conservative management strategies upon failure of other invasive approaches, especially in the absence of severe symptoms.
  • 3
    The patient's intradural SACs were conservatively managed during 3 years before surgical treatment.

Research Summary

Herein, we report on a rare case of multiple and recurring intradural spinal arachnoid cysts (SACs) causing severe spinal cord compression and neuropathic radicular pain, in a 35-year-old female with a 10-year follow-up. Two separate attempts at surgery were performed but only provided temporary relief since the cysts recurred and new ones formed along the entirety of the spinal cord. Finally, a conservative approach with physiotherapy and a combination of analgesic medications was pursued.

Practical Implications

Diagnostic Awareness

Consider spinal arachnoid cysts in patients with spinal cord and nerve root compression symptoms.

Treatment Strategy

Surgical treatment may be offered initially, but conservative management should be considered if recurrence is rapid and symptoms are not severe.

Etiological Investigation

Further research is needed to understand the etiology and potential genetic factors associated with multiple and recurring arachnoid cysts.

Study Limitations

  • 1
    Single case report limits generalizability.
  • 2
    Etiology of the multiple arachnoid cysts remains undefined.
  • 3
    Limited long-term data on conservative management outcomes.

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