Age-dependent effect of vitamin D supplementation on musculoskeletal health in chronic spinal cord injury patients: A pilot study

This study explores how vitamin D supplementation affects body composition and musculoskeletal health in individuals with chronic spinal cord injury (SCI) who also have vitamin D deficiency. The research divided participants into two age groups: those under 65 and those 65 and older, to see if age influenced the effects of vitamin D supplementation. The findings suggest that vitamin D supplementation has different benefits for younger and older adults with SCI, with both groups showing positive changes in body composition.

• 1
  In younger adults with SCI, vitamin D supplementation led to significant improvements in testosterone, total cholesterol, and triglyceride levels.
• 2
  In older adults with SCI, vitamin D supplementation significantly increased vitamin D and protein mass levels.
• 3
  Baseline clinical characteristics, including Skeletal Muscle Mass Index (SMI), Skeletal Muscle Mass (SMM), Soft Lean Mass (SLM), and Protein Mass (PM) were significantly better in the younger adult group.