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  4. A Primary Care Provider's Guide to Bone Health in Spinal Cord-Related Paralysis

A Primary Care Provider's Guide to Bone Health in Spinal Cord-Related Paralysis

Top Spinal Cord Inj Rehabil, 2020 · DOI: 10.46292/sci2602-128 · Published: January 1, 2020

Spinal Cord InjuryMusculoskeletal Medicine

Simple Explanation

Individuals with spinal cord injury/disorder (SCI/D) are at high risk for developing secondary osteoporosis. Bone loss after neurologic injury is multifactorial and is dependent on the time from and extent of neurologic injury. Most bone loss occurs in the first year after complete motor paralysis, and fractures occur most commonly in the distal femur and proximal tibia (paraplegic fracture). Clinicians caring for individuals with spinal cord–related paralysis must maintain a high index of suspicion for fragility fractures and consider referral for surgical evaluation and management.

Study Duration
Not specified
Participants
Individuals with spinal cord injury/disorder (SCI/D)
Evidence Level
Not specified

Key Findings

  • 1
    Most bone loss occurs in the first year following neurologic injury and continues for years after.
  • 2
    Spinal cord injury–related fractures occur most commonly around the knee (distal femur/proximal tibia).
  • 3
    All adults with spinal cord injury resulting in permanent motor or sensory dysfunction should have a DXA (dual-energy x-ray absorptiometry) scan of the total hip, proximal tibia, and distal femur as soon as medically stable in order to diagnose osteoporosis, predict lower extremity fracture risk, and monitor response to therapy.

Research Summary

Individuals with spinal cord injury/disorder (SCI/D) are at high risk for developing secondary osteoporosis, with bone loss being multifactorial and dependent on the time from and extent of neurologic injury. The 2019 International Society for Clinical Densitometry Position Statement in SCI establishes that dual-energy X-ray absorptiometry (DXA) can be used to both diagnose osteoporosis and predict lower extremity fracture risk in individuals with SCI/D. Clinicians caring for individuals with spinal cord–related paralysis must maintain a high index of suspicion for fragility fractures and consider referral for surgical evaluation and management.

Practical Implications

Early DXA Screening

Perform DXA scans on patients with SCI/D as soon as medically stable and regularly thereafter to monitor bone health.

Fracture Awareness

Maintain a high index of suspicion for fragility fractures, especially around the knee, in individuals with SCI/D.

Personalized Management

Consider recommending physical modalities and pharmacologic management to decrease bone resorption and/or increase bone deposition.

Study Limitations

  • 1
    Lack of established reference values for knee bone DXA.
  • 2
    FRAX tool is not validated for individuals with paralysis.
  • 3
    No established correlation between exercise, modalities, and fracture rates.

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