A possible effect of montelukast on neurological aging examined by the use of register data

This study investigates whether montelukast, a drug typically used for asthma, might have a positive effect on the aging brain. The researchers analyzed data from Norwegian registries to see if there's a connection between montelukast use and better neurological function in older adults. The study linked prescription data with results from neurological tests, comparing montelukast users to those using other immune-related drugs. They looked at factors like memory, balance, and finger tapping speed to assess brain health. The findings suggest that montelukast might help slow down age-related neurological decline. This idea comes from observing that montelukast users tended to score better on neurological tests compared to others, even after considering other health factors.

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  Previous use of montelukast correlated with improved scores on cognitive or neurological functioning.
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  Montelukast users showed significantly improved scores on the Short Physical Performance Battery (SPPB) and finger-tapping tests compared to the control group.
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  Other anti-inflammatory agents, such as NSAIDs and glucocorticoids, did not show the same positive correlation with cognitive or neurological function as montelukast.