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  4. A case of extramedullary subdural spindle cell hemangioendothelioma of the thoracic spinal cord treated curatively with radiation therapy

A case of extramedullary subdural spindle cell hemangioendothelioma of the thoracic spinal cord treated curatively with radiation therapy

Heliyon, 2023 · DOI: https://doi.org/10.1016/j.heliyon.2023.e18149 · Published: July 11, 2023

Oncology

Simple Explanation

Spindle cell hemangioendothelioma (SCH) is a very rare type of benign tumor. This paper reports a case of SCH located in the spinal cord that was successfully treated with a lower dose of radiation therapy than previously used. The patient, a 56-year-old man, presented with lower back pain and muscle weakness. After surgery to remove the tumor, some tumor remained, and he received radiation therapy. The patient's symptoms improved, and the tumor remained stable during follow-up. The study suggests that radiation therapy, even at a lower dose of 40Gy, can be an effective treatment for SCH in the spinal cord, particularly when surgery is not fully successful or feasible.

Study Duration
24 Months
Participants
One 56-year-old male
Evidence Level
Case Report

Key Findings

  • 1
    A radiation dose of 40Gy was effective in controlling the SCH tumor and preventing recurrence in this case.
  • 2
    Neurological symptoms returned to normal four months after radiotherapy and remained stable during the 24-month follow-up.
  • 3
    The study suggests that epidural lesions are more likely to occur in the upper segment of the thoracic spine, while intramedullary lesions are more likely in the middle segment, and extramedullary subdural lesions in the lower segment.

Research Summary

This case report describes a successful treatment of a rare spinal cord tumor, spindle cell hemangioendothelioma (SCH), with a lower dose of radiation therapy (40Gy). The patient, who had residual tumor after surgery, experienced a complete return of neurological function and no recurrence during the 24-month follow-up period. The authors conclude that a radiation dose of 40Gy can be effective for controlling SCH, reducing the risk of spinal cord injury, and that radiotherapy is a viable treatment option for inoperable or residual tumors.

Practical Implications

Reduced Radiation Dose

A lower radiation dose of 40Gy can be effective for treating spinal cord SCH, minimizing potential side effects.

Alternative Treatment Option

Radiotherapy can be a primary treatment method for patients with inoperable or residual spinal cord SCH, especially in functional areas.

Location Prediction

The location of SCH within the spinal cord may correlate with the specific spinal segment, aiding in diagnosis and treatment planning.

Study Limitations

  • 1
    Small sample size (single case report)
  • 2
    Relatively short follow-up period (24 months)
  • 3
    Lack of a systematically recognized standard treatment protocol due to the small number of cases

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