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  4. Wiltse transforaminal thoracic interbody fusion approach for the treatment of single‑segment thoracic spinal tuberculosis in elderly patients with osteoporosis: A retrospective study of 20 cases

Wiltse transforaminal thoracic interbody fusion approach for the treatment of single‑segment thoracic spinal tuberculosis in elderly patients with osteoporosis: A retrospective study of 20 cases

EXPERIMENTAL AND THERAPEUTIC MEDICINE, 2023 · DOI: 10.3892/etm.2023.11834 · Published: January 31, 2023

AgingOrthopedicsSpinal Disorders

Simple Explanation

This study investigates the effectiveness of the Wiltse TTIF surgical approach combined with anti-TB chemotherapy for elderly patients suffering from single-segment thoracic tuberculosis (SSTTB) complicated by osteoporosis and neurological problems. The Wiltse approach involves a surgical technique that reduces dissection time and traction of the multifidus muscle, taking advantage of the integrity of the posterior bone and ligamentous structural complexes. The study followed 20 elderly patients who underwent the Wiltse TTIF approach, assessing their kyphosis angle, neurological deficits, TB activity, and osteoporosis using various measurements and classifications.

Study Duration
24-48 months follow-up
Participants
20 elderly patients with single-segment thoracic tuberculosis and osteoporosis
Evidence Level
Retrospective study

Key Findings

  • 1
    The study found that all 20 patients with SSTTB were completely cured without recurrence after undergoing Wiltse TTIF surgery combined with anti-TB chemotherapy.
  • 2
    The postoperative kyphotic angle significantly improved, and bone graft fusion was observed within 6-9 months, with all patients reporting relief of back pain.
  • 3
    The neurological condition of all patients improved postoperatively, as assessed by the Frankel classification.

Research Summary

This study evaluated the clinical feasibility and efficacy of the Wiltse TTIF approach in elderly patients with single-segment thoracic tuberculosis complicated with osteoporosis and neurological dysfunction. The results showed that all patients were cured without recurrence, with significant improvement in kyphotic angle, bone fusion, and neurological condition. The study suggests that Wiltse TTIF surgery combined with anti-TB chemotherapy is a satisfactory treatment option for elderly patients with SSTTB complicated by osteoporosis and neurological impairment.

Practical Implications

Surgical treatment option

Wiltse TTIF can be considered a viable surgical option for elderly patients with SSTTB, osteoporosis, and neurological deficits.

Improved patient outcomes

The combination of Wiltse TTIF and anti-TB chemotherapy can lead to complete cure, pain relief, improved neurological function, and correction of kyphosis.

Reduced hospital stay

The Wiltse TTIF approach may contribute to shorter hospital stays compared to other surgical techniques for treating thoracic TB.

Study Limitations

  • 1
    The follow-up time was relatively short.
  • 2
    The study involved a small sample size of 20 patients.
  • 3
    The study was conducted at a single institution.

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