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  4. The patient‑related factors in revision procedures on tibia of patients with osteogenesis imperfecta treated with the Peter‑Williams nail

The patient‑related factors in revision procedures on tibia of patients with osteogenesis imperfecta treated with the Peter‑Williams nail

Journal of Orthopaedic Surgery and Research, 2023 · DOI: https://doi.org/10.1186/s13018-023-03952-w · Published: June 23, 2023

SurgeryOrthopedicsMusculoskeletal Medicine

Simple Explanation

This study investigates factors affecting the need for repeat surgeries on the tibia (shin bone) in patients with osteogenesis imperfecta (OI) who are treated with Peter-Williams nails. The study found that the age at the time of the initial surgery and the type of OI a patient has significantly influence the likelihood of needing a revision surgery. Specifically, patients with type III OI who had their initial surgery between the ages of 9 and 12 had a lower revision rate. The study also observed a higher occurrence of bone deformities after surgery in patients with type III OI.

Study Duration
96-120 Months
Participants
211 patients with osteogenesis imperfecta
Evidence Level
Retrospective analysis

Key Findings

  • 1
    The age of initial surgery significantly correlates with revision procedures (OR = 0.83, 95% CI 0.76–0.92, P < 0.001).
  • 2
    Classification of osteogenesis imperfecta significantly impacts revision procedures (OR = 3.32, 95% CI 1.06–10.39, P = 0.039).
  • 3
    In type III OI patients, initial operation age was significantly correlated with revision procedures (P < 0.001), with lower revision rates in those aged 9-12 years (P = 0.001).

Research Summary

This study explored patient-related factors affecting the revision procedures of tibia in patients with osteogenesis imperfecta treated with the Peter-Williams nail and investigated the relationship between the risk factors and complications. We found that the age at initial surgery and classification had a statistically significant influence on the revision rate, and the revision rate was lower for type III patients aged 9 to 12 years old. The study also reported a higher incidence of postoperative deformity in patients with type III OI.

Practical Implications

Optimal Surgical Timing

For individuals with type III osteogenesis imperfecta, performing the initial tibial surgery with Peter-Williams nails between the ages of 9 and 12 years may decrease the likelihood of needing future revision surgeries.

Type III OI Considerations

Surgeons should be aware of the increased risk of postoperative deformity in patients with type III OI when using Peter-Williams nails for tibial procedures.

Patient-Specific Approach

Treatment plans for osteogenesis imperfecta patients should consider both the patient's age at the time of initial surgery and the specific classification of their OI to optimize outcomes and minimize revision surgeries.

Study Limitations

  • 1
    Short to medium-term follow-up in some studies
  • 2
    Potential recall bias
  • 3
    Small number of patients

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