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  4. The Impact of Magnetic Resonance Imaging Findings in Predicting Neurological Status Pre- and Post-Treatment of Spinal Dural Arteriovenous Fistulas: A 22-Year Experience in a Neurovascular and Spine Center

The Impact of Magnetic Resonance Imaging Findings in Predicting Neurological Status Pre- and Post-Treatment of Spinal Dural Arteriovenous Fistulas: A 22-Year Experience in a Neurovascular and Spine Center

Diagnostics, 2024 · DOI: 10.3390/diagnostics14060581 · Published: March 8, 2024

NeuroimagingNeurologySpinal Disorders

Simple Explanation

Spinal dural arteriovenous fistulas (SDAVF) involve abnormal connections between arteries and veins in the spine, leading to venous hypertension and myelopathy. MRI is commonly used to monitor SDAVF, but the significance of MRI signs like myelopathy and flow voids in predicting patient outcomes is debated. This study investigates the predictive value of MRI findings before and after treatment of SDAVF and their correlation with the patient's neurological status.

Study Duration
22 Years
Participants
81 patients initially, with 41 SDAVF patients having follow-up MRI included
Evidence Level
Not specified

Key Findings

  • 1
    Pretreatment ASIA-MS (motor score) correlated with the extent of myelopathy at admission, indicating a relationship between motor function and spinal cord damage.
  • 2
    Post-treatment MRI changes, such as the resolution of myelopathy or flow voids, did not correlate with clinical outcomes.
  • 3
    Diagnostic sensitivity of magnetic resonance angiography (MRA) for localization of the fistula was 68.3%.

Research Summary

This study analyzed the clinical records of 81 patients who underwent surgical or endovascular treatment for SDAVF. The study found that the severity of motor deficits correlated with the extent of myelopathy on pretreatment MRI, but post-treatment MRI changes did not correlate with clinical outcomes. The diagnostic sensitivity of MRA to locate the fistula was 68.3%.

Practical Implications

Diagnostic Utility of MRA

MRA can be used as a non-invasive method to narrow down the potential localization in advance and should be used to reduce the radiation exposure of angiography.

Prognostic Value of MRI

MRI changes after treatment should not be used as a prognostic factor for clinical outcome in SDAVF patients.

Multifactorial Clinical Condition

The clinical condition of SDAVF patients is influenced by multiple factors, and motor deficits are related to the extent of myelopathy.

Study Limitations

  • 1
    Monocentric, retrospective design
  • 2
    Long inclusion interval
  • 3
    Limited number of SDAVF patients (41 patients)

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