Protein expression of sensory and motor nerves: Two-dimensional gel electrophoresis and mass spectrometry

This study used a method called two-dimensional gel electrophoresis and mass spectrometry to look at the proteins found in motor and sensory nerves. The scientists found that some proteins were more common in motor nerves, while others were more common in sensory nerves. These differences in protein levels may help explain how these nerves regenerate after an injury and could potentially be used to improve nerve repair strategies.

• 1
  Differential expression of 11 proteins was observed between motor and sensory nerves.
• 2
  Transgelin was found to be upregulated in saphenous nerve tissues compared to motor branches of the femoral nerve.
• 3
  Aldose reductase and a glyceraldehyde-3-phosphate dehydrogenase (GAPDH)-like protein were significantly increased in the motor branch of the femoral nerve compared to the saphenous nerve.