Intramedullary Spinal Hemorrhage in Behcet’s Syndrome: A Case Report and Systematic Review

Behcet's syndrome (BS) is a systemic vasculitis affecting arterial and venous vessels of all sizes, resulting in a broad array of clinical manifestations. Neurological involvement is rare, but when it occurs, it is often accompanied by severe disability and significant morbidity and mortality. The diversity of clinical manifestations proves challenging for early diagnosis; therefore, timely management is of paramount importance to compensate for the severity of progression at the time of presentation.

• 1
  The case presents the first reported instance of an abrupt onset of neurological injury secondary to intramedullary spinal cord bleed in Behcet’s syndrome.
• 2
  The systematic review demonstrates no difference in mortality for patients managed conservatively compared to those who undergo surgical treatment.
• 3
  New-onset neurological findings in patients with Behcet’s syndrome should raise suspicion for possible spontaneous hemorrhage.