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  4. Image-Guided Stereotactic Radiosurgery for the Treatment of Spasticity and Pain: A Preliminary Experience

Image-Guided Stereotactic Radiosurgery for the Treatment of Spasticity and Pain: A Preliminary Experience

Cureus, 2022 · DOI: 10.7759/cureus.24021 · Published: April 11, 2022

NeurologySurgeryRehabilitation

Simple Explanation

This study explores a new method to treat spasticity and pain using stereotactic radiosurgery. It focuses on targeting the spinal roots with precise radiation to relieve symptoms. The procedure involves using image guidance to direct radiation to specific areas of the spinal nerve roots. This is done to disrupt the signals causing spasticity and pain. The early results suggest that this technique is safe and can significantly reduce spasticity and pain in patients. This offers a non-invasive alternative to surgery.

Study Duration
2 Years
Participants
4 patients with refractory spasticity and related pain
Evidence Level
Not specified

Key Findings

  • 1
    All treated patients experienced marked symptomatic relief.
  • 2
    The average reduction in pain, measured by the visual analog scale (VAS), was 64.3% after two years.
  • 3
    The median reduction of the Modified Ashworth Scale (MAS) score, used to assess spasticity, was 50% after two years.

Research Summary

This study introduces a novel, noninvasive technique using image-guided radiosurgery to treat severe spasticity and pain resulting from brain and spinal cord injuries. The treatment targets the cervical or lumbar spinal roots, focusing irradiation on specific sensory segments to relieve spasticity and pain. The results indicate that this technique is safe, effective, and warrants further investigation as a potential treatment option.

Practical Implications

Non-invasive Alternative

Offers a non-invasive alternative to surgical interventions like selective dorsal rhizotomy (SDR) or intrathecal baclofen pump placement for managing spasticity and pain.

Cost-Effective Treatment

Image-guided frameless SRS is highlighted as a cost-effective procedure, potentially expanding access to treatment for patients in regions with limited resources.

Improved Patient Outcomes

The study suggests the potential for improved patient outcomes through the reduction of spasticity and pain, enhancing the quality of life for individuals suffering from neurological injuries.

Study Limitations

  • 1
    Small sample size of only four patients.
  • 2
    The heterogeneous origin of spasticity among the patients.
  • 3
    Requires prospective studies on a larger cohort to assess toxicity.

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