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  4. Guillain-Barré Syndrome with Respiratory Failure following Spine Surgery for Incomplete Cervical Cord Injury: A Case Report and Literature Review

Guillain-Barré Syndrome with Respiratory Failure following Spine Surgery for Incomplete Cervical Cord Injury: A Case Report and Literature Review

Medicina, 2022 · DOI: 10.3390/medicina58081063 · Published: August 6, 2022

NeurologySurgeryRehabilitation

Simple Explanation

Guillain-Barré syndrome (GBS) is a condition where the body's immune system attacks the nerves. This often happens after a respiratory or gastrointestinal infection. This paper presents a case of an 87-year-old man who developed GBS after undergoing spine surgery for a cervical spinal cord injury. The patient's condition worsened, leading to respiratory failure and ventilator dependence, highlighting the importance of considering GBS in patients with spinal cord injuries who experience postoperative weakness.

Study Duration
Not specified
Participants
An 87-year-old man
Evidence Level
Level 4: Case Report and Literature Review

Key Findings

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    The patient developed GBS after spinal surgery, presenting with progressive limb weakness and paresthesia.
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    CSF studies revealed albuminocytologic dissociation, and NCS indicated acute axonal polyneuropathy.
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    The patient's family declined immune-modulatory therapy, and he progressed to respiratory failure, remaining ventilator-dependent until his death three years later.

Research Summary

This case report describes an uncommon occurrence of Guillain-Barré syndrome (GBS) following spinal surgery in an 87-year-old man with a traumatic cervical spinal cord injury. The patient experienced progressive muscle weakness, leading to paralysis and respiratory failure, and ultimately required long-term ventilator support. The case emphasizes the importance of considering GBS in patients with spinal cord injuries who present with postoperative weakness, as early diagnosis and treatment are crucial for improved prognosis.

Practical Implications

Clinical Awareness

Clinicians should be aware of the possibility of GBS in patients with spinal cord injuries who develop new or worsening weakness after surgery.

Early Diagnosis

Prompt diagnostic evaluation, including CSF analysis and nerve conduction studies, is crucial for early detection of GBS.

Timely Treatment

Early administration of immunomodulatory therapy, such as IVIG or plasmapheresis, may improve outcomes in patients with GBS following spinal surgery.

Study Limitations

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