Effectiveness and safety analysis of titanium mesh grafting versus bone grafting in the treatment of spinal Tuberculosis: a systematic review and meta-analysis

BMC Surgery, 2023 · DOI: https://doi.org/10.1186/s12893-023-02283-1 · Published: December 5, 2023

Simple Explanation

Spinal tuberculosis can lead to complications like spinal cord injury and deformities. Surgery helps remove lesions, relieve compression, correct deformities, and restore stability. This study compares titanium mesh and bone grafts for spinal tuberculosis surgery. It looks at how well each works and how safe they are. The study combines the results of multiple studies to get a better understanding. It looks at things like surgery time, blood loss, and how long it takes for the bone to heal.

Study Duration

Not specified

Participants

523 patients

Evidence Level

Level 3: Meta-analysis of observational studies

Key Findings

1
There's no significant difference in surgery duration between titanium mesh and bone grafting.
2
There's no significant difference in intraoperative blood loss between the two methods.
3
Bone grafting had a slightly lower rate of postoperative implant subsidence compared to titanium mesh grafting.

Research Summary

This study compares titanium mesh and bone grafting for spinal tuberculosis. The results show both methods are effective and safe. There were no significant differences in surgical duration, blood loss, fusion time, spinal cord injury assessment, or overall complications. Bone grafting had a slightly lower rate of implant subsidence.

Practical Implications

Surgical Choice

Surgeons can choose either titanium mesh or bone grafting based on patient needs and resources, as both are similarly effective.

Resource Allocation

In areas with limited resources, bone grafting remains a viable option due to its effectiveness and lower cost.

Subsidence Prevention

When using titanium mesh, surgeons should take measures to prevent implant subsidence, as this complication was more common with this method.

Study Limitations

1
All included studies were non-randomized controlled experiments, which are susceptible to bias.
2
Some studies had small sample sizes, making it difficult to determine differences in outcomes for some complications.
3
Many studies did not provide detailed records of the location and number of affected segments.

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