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  4. Earlier consolidation and improved knee function of medial open wedge high tibial osteotomy with autologous bone graft

Earlier consolidation and improved knee function of medial open wedge high tibial osteotomy with autologous bone graft

European Journal of Orthopaedic Surgery & Traumatology, 2024 · DOI: https://doi.org/10.1007/s00590-023-03656-1 · Published: August 4, 2023

Orthopedics

Simple Explanation

Medial knee osteoarthritis can be treated with medial open wedge high tibial osteotomy (OWHTO). This study investigates osseous consolidation of the osteotomy with and without autologous bone grafts (ABG) to detect possible benefits of ABG in osseous healing and functional outcome. The study found that autologous bone grafting resulted in earlier osseous consolidation after medial OWHTO and showed a tendency to a better functional outcome.

Study Duration
12 Months
Participants
35 patients undergoing medial OWHTO
Evidence Level
Prospective study

Key Findings

  • 1
    Radiologic evaluation showed a significantly earlier consolidation of the osteotomy gaps in patients with ABG.
  • 2
    A significantly higher rate of consolidation 12 months after surgery was observed in patients with ABG (100% vs. 60%).
  • 3
    A tendency to better function and less pain in patients with ABG was recognizable.

Research Summary

This prospective study evaluated the use of ABG in osteotomy gaps of medial OWHTO and the influence of grafting on postoperative knee function. The study found that bone grafting resulted in an earlier consolidation of the osteotomy gap and seemed to increase complete osseous union, with a tendency toward better functional outcomes after one year. CEUS and DCE-MRI showed physiological perfusion of the osteotomy gaps in both groups, controlling for confounding risk factors.

Practical Implications

Improved Consolidation

Autologous bone grafting can lead to earlier and more complete consolidation of the osteotomy gap in medial OWHTO.

Potential for Better Functional Outcomes

There is a tendency towards improved knee function and reduced pain in patients receiving ABG.

Consideration for High-Risk Patients

ABG may be particularly beneficial in patients with nicotine abuse or other risk factors for impaired bone healing.

Study Limitations

  • 1
    Small sample size
  • 2
    Evaluation of consolidation only by x-ray
  • 3
    Different donor locations

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