Concomitant Use of Neuroprotective Drugs in Neuro Rehabilitation of Multiple Sclerosis

Neurorehabilitation helps patients to reach and maintain their optimal physical, psychological and intellectual, levels but it does not reverse long-term disabilities that arise from neurological disorders. This calls for the need of better neuroregenerative and neuroprotective treatment strategies in addition to neurorehabilitation. Inclusion of these drugs as a multifaceted approach may further enhance the efficacy of neurorehabilitation in neuroinflammatory and neurodegenerative disorders.

• 1
  Inpatient rehabilitation is more likely prone to have short term effects on the activities and participation of MS patients but not on impairment.
• 2
  The early steps of neuronal plasticity are not likely to limit compensatory changes in MS and therefore there is a need for rehabilitation efforts on mechanisms supporting the late stages of motor learning
• 3
  After 5 weeks of cognitive training, patients demonstrated a significant clinical improvement of neuropsychological performance, and this corresponded with increased brain fMRI activity in cerebellar areas of the brain