Clinical Characteristics and Management of Ovarian Vein Thrombosis: A Case Series

Frontiers in Cardiovascular Medicine, 2022 · DOI: 10.3389/fcvm.2022.916920 · Published: June 16, 2022

Simple Explanation

Ovarian vein thrombosis (OVT) is an uncommon condition, especially after pregnancy. It can be related to blood clotting disorders, infections, surgeries, or cancer. This study looks at the factors linked to OVT and how it is usually treated. The study reviewed the medical records of 18 patients diagnosed with OVT between 2005 and 2016. The researchers collected information on patient characteristics, symptoms, risk factors, and treatment approaches. The study found that OVT is more common in the right ovarian vein and often occurs after childbirth. Patients typically experience abdominal pain and fever. Treatment with a blood thinner called enoxaparin for one to three months was found to be effective.

Study Duration

2005-2016

Participants

18 patients diagnosed with OVT

Evidence Level

Case Series

Key Findings

1
OVT involves the right ovarian vein more often than the left.
2
OVT mainly occurs in women during their postpartum period.
3
The most common treatment was the administration of enoxaparin for an average duration of one to three months, which resulted in a low recurrence rate of OVT.

Research Summary

This study examined 18 cases of ovarian vein thrombosis (OVT) to identify clinical characteristics, associated factors, and management strategies. Data was collected retrospectively from patients diagnosed with OVT between 2005 and 2016. The study found that OVT most commonly affects the right ovarian vein and occurs in the postpartum period. Common symptoms included abdominal pain and fever. Associated factors included hypertension and diabetes. Treatment with enoxaparin for one to three months was the most frequent intervention and resulted in a low recurrence rate. The authors suggest that physicians should consider OVT in postpartum women presenting with lower abdominal pain and fever.

Practical Implications

Clinical Vigilance

Physicians should be aware of OVT in postpartum women with abdominal pain and fever.

Treatment Strategy

Low molecular weight heparin (enoxaparin) is an effective initial therapy for OVT.

Further Research

Multi-center case-control studies are needed to confirm these findings.

Study Limitations

1
Retrospective design
2
Single-center data collection limiting sample size
3
Lack of a control group for comparison

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