Case report: Clinical highlights and radiological classification of IgG4-related spinal pachymeningitis: A rare case series and updated review of the literature

This study focuses on IgG4-related spinal pachymeningitis (IgG4-RSP), a rare condition where the spinal cord's protective layers thicken due to an immune response. The research presents three new cases and reviews existing literature to understand the disease's clinical features, radiological manifestations, treatment approaches, and patient outcomes. The paper aims to improve the diagnosis and treatment of IgG4-RSP by analyzing radiological findings and lesion locations.

• 1
  Progressive worsening of neurological impairment was observed in nearly half of the patients (48.9%).
• 2
  The thoracic and cervical spine were the most frequently involved segments.
• 3
  Early surgical decompression, corticosteroid treatment, and steroid-sparing agents offered significant therapeutic advantages.