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  4. Brain Activation Evoked by Motor Imagery in Pediatric Patients with Complete Spinal Cord Injury

Brain Activation Evoked by Motor Imagery in Pediatric Patients with Complete Spinal Cord Injury

AJNR Am J Neuroradiol, 2023 · DOI: http://dx.doi.org/10.3174/ajnr.A7847 · Published: May 1, 2023

NeuroimagingNeurologyPediatrics

Simple Explanation

This study investigates the brain activity of children with complete spinal cord injuries while they imagine moving. Researchers used fMRI to compare the brain activity of these children to that of healthy children when both groups were imagining movement. The study found that certain brain areas related to movement and thinking were still active in the children with spinal cord injuries during motor imagery. Furthermore, some sensorimotor areas showed higher activation levels in the injured children compared to the healthy children. These findings suggest that motor imagery could be a useful rehabilitation technique for children with complete spinal cord injuries, as it can activate preserved neural pathways and potentially promote brain reorganization.

Study Duration
2-108 months
Participants
26 pediatric patients with complete spinal cord injury and 26 healthy children
Evidence Level
Not specified

Key Findings

  • 1
    Motor-related and cognitive-related brain areas were functionally preserved in pediatric patients with complete spinal cord injury during motor imagery.
  • 2
    Pediatric patients with complete spinal cord injury showed higher activation in sensorimotor-related regions (bilateral paracentral lobule, supplementary motor area, putamen, and cerebellar lobules III–V) during motor imagery compared to healthy controls.
  • 3
    The activation of some of these regions in pediatric patients with complete spinal cord injury during motor imagery was even higher than that of healthy controls during motor execution.

Research Summary

This study explored the potential neural mechanism of motor imagery in the rehabilitation of pediatric patients with complete spinal cord injury using task-based fMRI. The results demonstrated that motor- and cognitive-related areas in the motor imagery network can be functionally preserved in pediatric patients after complete spinal cord injury. Higher-level activation in sensorimotor-related regions, reflecting functional reorganization, was also detected, providing a theoretic basis for applying motor imagery training in pediatric complete spinal cord injury.

Practical Implications

Rehabilitation Strategy

Motor imagery training may be a viable rehabilitation strategy for pediatric patients with complete spinal cord injury due to the functional preservation and reorganization observed in the motor imagery network.

Neural Reorganization Insights

The study provides insights into the neural mechanisms underlying motor imagery in pediatric complete spinal cord injury, highlighting the potential for functional reorganization in sensorimotor-related regions.

Future Research Directions

The findings suggest the need for further longitudinal studies to confirm the long-term effects of motor imagery training on pediatric patients with complete spinal cord injury.

Study Limitations

  • 1
    Pediatric patients with complete spinal cord injury in the current study had varying disease durations.
  • 2
    This study was a cross-sectional study.
  • 3
    A future longitudinal study is required to confirm the effect of motor imagery on pediatric patients with complete spinal cord injury.

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