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  4. Assessment of Cervical Myelopathy Risk in Ossification of the Posterior Longitudinal Ligament Patients With Spinal Cord Compression Based on Segmental Dynamic Versus Static Factors

Assessment of Cervical Myelopathy Risk in Ossification of the Posterior Longitudinal Ligament Patients With Spinal Cord Compression Based on Segmental Dynamic Versus Static Factors

Neurospine, 2023 · DOI: https://doi.org/10.14245/ns.2346124.062 · Published: June 1, 2023

NeurologyOrthopedicsSpinal Disorders

Simple Explanation

This study examines the relationship between ossification of the posterior longitudinal ligament (OPLL) and the severity of cervical myelopathy using both static and dynamic factors in the cervical spine. The research investigates how factors like spinal canal space, cervical spine alignment, and range of motion at different segments of the cervical spine contribute to the development of myelopathy in OPLL patients. The study aims to provide a more comprehensive understanding of the risk factors for myelopathy in OPLL patients, which can help improve clinical treatment strategies.

Study Duration
2012 to 2014
Participants
163 OPLL patients
Evidence Level
Not specified

Key Findings

  • 1
    Minimal space available for the spinal cord (SAC), C2–7 Cobb angle, total range of motion (ROM), and local ROM were identified as independent predictors of myelopathy in OPLL patients.
  • 2
    Patients with myelopathy had a straighter whole cervical spine and poorer cervical mobility compared to those without myelopathy.
  • 3
    Hypermobility of the C2–3 and C3–4 segments contributes significantly to the development of myelopathy in OPLL.

Research Summary

This study assessed the relationship between static and dynamic factors and the severity of cervical myelopathy in OPLL patients. The study found that minimal SAC, Cobb angle, total ROM, and local ROM were independent predictors of myelopathy. The hypermobility of the upper cervical spine was also a contributing factor. The authors conclude that understanding these segmental factors is crucial for improving clinical treatment for OPLL patients.

Practical Implications

Improved Risk Assessment

Identifying key factors such as minimal SAC and ROM helps in better assessing the risk of myelopathy in OPLL patients.

Targeted Treatment Strategies

Understanding the role of upper cervical instability can lead to more targeted treatment strategies.

Personalized Management

Considering both static and dynamic factors allows for a more personalized approach to managing OPLL patients.

Study Limitations

  • 1
    Retrospective and cross-sectional study design.
  • 2
    Small sample size from a single institute.
  • 3
    Lack of 3D-CT, dynamic CT, or MRI for retrospective analysis.

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