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  4. A traditional Chinese herbal formula improves pressure ulcers in paraplegic patients: A randomized, parallel-group, retrospective trial

A traditional Chinese herbal formula improves pressure ulcers in paraplegic patients: A randomized, parallel-group, retrospective trial

EXPERIMENTAL AND THERAPEUTIC MEDICINE, 2013 · DOI: 10.3892/etm.2013.1053 · Published: January 26, 2013

Alternative MedicineDermatology

Simple Explanation

This study examined if a new Chinese herbal ointment called cure rot and flat sore ointment (CRFSO) helps treat stage IV pressure ulcers in paraplegic patients. It also looked at whether rehabilitation alongside the ointment improves results. The study compared CRFSO to Arnebia root oil (ARO), another treatment. The results showed that CRFSO was more effective in healing pressure sores in these patients. The herbal formula effectively improved pressure sores, and rehabilitation further enhanced the improvement.

Study Duration
6 Years
Participants
35 paraplegic patients
Evidence Level
Level 2: Randomized, parallel-group, retrospective trial

Key Findings

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    CRFSO demonstrated a significantly higher healing rate (85%) compared to ARO (45.45%) after 28 days of treatment.
  • 2
    The 'no response rate' was significantly lower in the CRFSO group (5%) compared to the ARO group (18.18%).
  • 3
    Treatment with CRFSO resulted in a shorter therapeutic duration (mean 19.47 days) compared to ARO (mean 29.18 days).

Research Summary

This study evaluated the effectiveness of a novel Chinese herbal formula, CRFSO, in treating stage IV pressure ulcers in paraplegic patients and the impact of simultaneous comprehensive rehabilitation. The study found that CRFSO was more effective than ARO in terms of healing rate, effectiveness rate, improvement rate, and no response rate after 28 days of treatment. The researchers concluded that CRFSO is a promising treatment for pressure ulcers in paraplegic patients, and inpatient rehabilitation further improved outcomes.

Practical Implications

Effective Treatment Option

CRFSO presents a potentially more effective treatment option for stage IV pressure ulcers in paraplegic patients compared to ARO.

Integrated Approach

Combining CRFSO treatment with inpatient rehabilitation may lead to improved outcomes for patients with pressure ulcers.

Traditional Medicine Validation

This study provides evidence supporting the use of traditional Chinese medicine in the treatment of chronic wounds like pressure ulcers.

Study Limitations

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